Ashwagandha para Dificuldade para Adormecer

Q: Does Ashwagandha help with Dificuldade para Adormecer?

Based on 6 studies with 454 participants, there is moderate evidence from clinical studies that Ashwagandha may support Dificuldade para Adormecer management. Our evidence grade is B (Good Evidence).

Q: How much Ashwagandha should I take for Dificuldade para Adormecer?

Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Ashwagandha and Dificuldade para Adormecer?

We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 454 total participants. The overall direction of effect is positive.

Baseado em 6 estudos (3 RCTs) com 454 participantes no total. 6/6 estudos mostram efeitos positivos.

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Conclusão

Research suggests ashwagandha may help you fall asleep faster, with multiple well-designed clinical trials consistently showing reduced time to fall asleep.

All 6 studies show positive effects, including 3 RCTs with 454 total participants
A 2024 meta-analysis confirmed benefits for sleep onset
Active compound triethylene glycol from ashwagandha leaves has been identified as a sleep-inducing agent
Benefits observed in both healthy adults and people diagnosed with insomnia

Key Study Findings

systematic review and meta-analysis n=254

Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis.

Dose: varies across included RCTs vs: Placebo Efeito: HAM-A MD = -5.96 (95% CI -10.34, -1.59); significant improvements in SOL, TST, PSQI, SE; no signific 0.008 (HAM-A)

animal_study

Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in …

Dose: 10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden) vs: Placebo Efeito: At 50 mg/kg: 34% decrease in sleep onset time (p<0.0001); 47% increase in sleep duration (p<0.0001); <0.0001

Randomized Controlled Trial n=80 8 weeks Double-blind

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers …

Dose: None vs: Placebo Efeito: None SOL p=0.013; HAM-A p<0.05; men

RCT n=60 4 weeks Open-label

Efficacy of Brimhana Nasya and Ashwagandha (Withania somnifera (L.) Dunal) root powder in primary insomnia …

Dose: None vs: Placebo Efeito: None p<0.0001

Randomized Controlled Trial n=60 10 weeks Double-blind

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, …

Dose: 300 mg twice daily vs: Placebo Efeito: SOL: 29.00 vs 33.94 min (placebo) at 10 weeks; SE: 83.48 vs 79.68 p=0.019 (SOL); p=0.002 (sleep

In Vitro

Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction.

Dose: 10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves vs: Placebo Efeito: Significant increase in NREM sleep in a dose-dependent manner None

Key Statistics

Estudos

454

Participantes

↑

Positive

Nota

Referenced Papers

Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis. Meta-Analysis

Human psychopharmacology 2024 9 citações

Hydroalcoholic Extract of Ashwagandha Improves Sleep by Modulating GABA/Histamine Receptors and EEG Slow-Wave Pattern in In Vitro - In Vivo … Other

Preventive nutrition and … 2022 18 citações

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, … RCT

Journal of ethnopharmacology 2021 58 citações

Efficacy of Brimhana Nasya and Ashwagandha (Withania somnifera (L.) Dunal) root powder in primary insomnia in elderly male: A randomized … Other

Ayu 2020 5 citações

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Other

Cureus 2019 101 citações

Triethylene glycol, an active component of Ashwagandha (Withania somnifera) leaves, is responsible for sleep induction. Other

PloS one 2017 57 citações

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosagens Comumente Utilizadas

sleep:: 300-600 mg KSM-66 or Sensoril, before bed

Limite superior: Not established; studied up to 1,200 mg/day

Dosagens Estudadas em Pesquisas

Dosagem	Duração	Efeito	N
varies across included RCTs	--	Positive	254
10, 25, or 50 mg/kg body weight ashwagandha extract (AE, 35% withanolide glycosides, Shoden)	--	Positive	--
None	8 weeks	Positive	80
None	4 weeks	Positive	60
300 mg twice daily	10 weeks	Positive	60
10-30 mg/mouse (triethylene glycol); water extract of Ashwagandha leaves	--	Positive	--

Melhor horário: 1-2 hours before bed

Safety & Side Effects

Efeitos Colaterais Relatados

⚠ Drowsiness
⚠ GI upset
⚠ Diarrhea
⚠ Headache

Interações Conhecidas

● Thyroid medications — ashwagandha may increase thyroid hormone levels
● Immunosuppressants — ashwagandha may stimulate immune activity
● Sedatives — potential additive drowsiness
● Blood sugar medications — may lower blood glucose

Ingestão máxima tolerável: Not established; studied up to 1,200 mg/day

Consulte sempre o seu profissional de saúde antes de iniciar qualquer suplemento.Sempre consulte seu profissional de saúde antes de iniciar qualquer suplemento.

Frequently Asked Questions

Does Ashwagandha help with Dificuldade para Adormecer?

Based on 6 studies with 454 participants, there is moderate evidence from clinical studies that Ashwagandha may support Dificuldade para Adormecer management. Our evidence grade is B (Good Evidence).

How much Ashwagandha should I take for Dificuldade para Adormecer?

Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Ashwagandha?

Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Ashwagandha and Dificuldade para Adormecer?

We rate the evidence as Grade B (Good Evidence). This rating is based on 6 peer-reviewed studies with 454 total participants. The overall direction of effect is positive.

Related Evidence

Outros ingredientes para Dificuldade para Adormecer

Magnesium Glycinate A Vitamina B6 A Zinco A Melatonina A Hops A L-Theanine A

Ashwagandha para outras condições

Insônia A Problemas de Sono Relacionados à Ansiedade B

Veredito Rápido

Baseado em 6 estudos (3 RCTs) com 454 participantes no total. 6/6 estudos mostram efeitos positivos.

Evidence Strength72%

High confidence

Detalhamento dos Estudos

RCT (1)Meta (1)Other (4)

Comparar Alternativas

Veja como outros ingredientes se comparam para esta condição.

Ver todos os ingredientes para Dificuldade para Adormecer

Saiba Mais

Aviso Legal da FDA: Estas declarações não foram avaliadas pela Food and Drug Administration. Os produtos e informações neste site não se destinam a diagnosticar, tratar, curar ou prevenir qualquer doença. As notas de evidência apresentadas são baseadas em nossa análise de pesquisas revisadas por pares publicadas e não constituem aconselhamento médico. Sempre consulte seu profissional de saúde antes de iniciar qualquer regime de suplementação.