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Kava per Insonnia

A

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

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A

In sintesi

Based on 34 studies (8 meta-analyses, 1 RCT) with 4,679 total participants. Results are mixed across studies.

Key Study Findings

Case Reports n=1 6 weeks
Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption.
Dose: None vs: None Outcome: acute kava dermopathy with sebaceous gland necrosis Effetto: None None

Popolazione: 41-year-old Australian woman consuming kava for anxiety and insomnia

Case Reports n=1 Open-label
Severe kava withdrawal managed with phenobarbital.
Dose: None vs: None Outcome: Resolution of kava withdrawal symptoms Effetto: None None

Popolazione: 45-year-old man with kava and kratom withdrawal

narrative review
Herbal and Natural Supplements for Improving Sleep: A Literature Review.
Dose: varies by supplement vs: Placebo Effetto: None None
Other Double-blind
The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and …
Dose: AB-free kava extract vs: Placebo Outcome: Tobacco cessation via stress/insomnia management Effetto: None None

Popolazione: Adult smokers (trial protocol)

Key Statistics

34

Studi

4679

Partecipanti

Mixed

A

Grado

Referenced Papers

The American journal … 2025 1 citazioni
Journal of psychosocial … 2022 2 citazioni
Combinatorial chemistry & … 2021 16 citazioni
Chemical research in … 2019 6 citazioni
Journal of medicinal … 2018 19 citazioni
Sleep medicine reviews 2015 152 citazioni
Advances in pharmacological … 2011 79 citazioni
Integrative cancer therapies 2004 59 citazioni
Human psychopharmacology 2003 45 citazioni
Primary care 2002 43 citazioni
Phytotherapy research : … 2001 74 citazioni
Psychosomatic medicine 1999 136 citazioni

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosaggi di uso comune

sleep:
120-250 mg kavalactones/day, 1-2 hrs before bed

Limite massimo: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Dosaggi studiati nella ricerca

Dosaggio Durata Effetto N
None 6 weeks Negative 1
None -- Positive --
None -- Positive 1
varies by supplement -- Positive --
AB-free kava extract -- Mixed --
various -- Mixed 17
None -- Mixed --
Various medicinal herbs: Silexan, Kava, Ginkgo biloba, Withania somnifera, Galphimia glauca, Passion -- Positive --

Momento migliore per l'assunzione: 1-2 hours before bed; avoid daily use beyond 3 months without medical supervision

Safety & Side Effects

Effetti collaterali segnalati

  • Drowsiness and reduced coordination
  • Hepatotoxicity (rare but serious — consult healthcare provider)
  • Skin rash (kava dermopathy) with chronic high-dose use
  • GI discomfort

Interazioni note

  • Alcohol — increased hepatotoxicity risk and CNS depression
  • Hepatotoxic medications (acetaminophen, statins) — additive liver stress
  • Benzodiazepines and sedatives — additive CNS depression
  • CYP450 substrates (2E1, 1A2, 2D6) — kavalactones may inhibit metabolism
  • Levodopa and dopaminergic drugs — kava may reduce efficacy

Livello di assunzione massimo tollerabile: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Consultare sempre il proprio medico prima di iniziare qualsiasi integratore.Consultate sempre il vostro medico prima di iniziare qualsiasi integratore.

Frequently Asked Questions

Does Kava help with Insonnia?
Based on 34 studies with 4,679 participants, there is strong evidence from multiple clinical trials that Kava may support Insonnia management. Our evidence grade is A (Strong Evidence).
How much Kava should I take for Insonnia?
Studies have used various dosages. A commonly studied range is 120-250 mg kavalactones/day, 1-2 hrs before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Kava?
Reported side effects may include Drowsiness and reduced coordination, Hepatotoxicity (rare but serious — consult healthcare provider), Skin rash (kava dermopathy) with chronic high-dose use, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Kava and Insonnia?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 34 peer-reviewed studies with 4,679 total participants. The overall direction of effect is mixed.

Related Evidence

Avvertenza FDA: Queste affermazioni non sono state valutate dalla Food and Drug Administration. I prodotti e le informazioni presenti su questo sito web non sono destinati a diagnosticare, trattare, curare o prevenire alcuna malattia. I gradi di evidenza presentati si basano sulla nostra analisi della ricerca pubblicata e sottoposta a revisione paritaria e non costituiscono consulenza medica. Consultate sempre il vostro medico prima di iniziare qualsiasi regime di integrazione.