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Vitamin B6 के लिए अनिद्रा

B

5 अध्ययनों (1 RCT) पर आधारित, में कुल 50 प्रतिभागियों के साथ। 3/5 अध्ययन सकारात्मक प्रभाव दिखाते हैं।

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B

निष्कर्ष

Vitamin B6 may play a role in supporting sleep through its involvement in melatonin production, but the direct evidence for insomnia is limited and preliminary.

  • Only 5 studies with 50 total participants — evidence is preliminary
  • B6 is involved in producing serotonin and melatonin, both important for sleep
  • Genetic studies (Mendelian randomization) suggest a link between B6 and sleep behaviors
  • More clinical trials with larger sample sizes are needed

Key Study Findings

Other
Causal relations of trace elements and nutrients with insomnia: A Mendelian randomization study.
Dose: None बनाम: None Outcome: Causal association of nutrients with insomnia प्रभाव: Magnesium OR 0.869 (95% CI 0.763-0.990) P<0.05

जनसंख्या: FinnGen insomnia GWAS population

review
[Nutrition in improving sleep quality and fighting insomnia].
Dose: tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral बनाम: Placebo प्रभाव: None None
Mendelian randomization
Genetically Supported Causality Between Micronutrients and Sleep Behaviors: A Two-Sample Mendelian Randomization Study.
Dose: None बनाम: Placebo प्रभाव: Folate vs chronotype OR 1.09 (95% CI 1.01-1.17); Vitamin B6 vs chronotype OR 0.91 (95% CI 0.86-0.96) Folate p=0.02; Vitamin B6 p=1.
prospective single-arm open-label pilot study n=40 4 weeks Open-label
A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: …
Dose: not specified per component बनाम: Placebo प्रभाव: mean sleep quality +1.9 points p < 0.001
Review
Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not?
Dose: None बनाम: None Outcome: None प्रभाव: None None

जनसंख्या: Crohn's disease patients (micronutrient deficiency)

Review
Strategies of Functional Foods Promote Sleep in Human Being.
Dose: None बनाम: None Outcome: Sleep quality and insomnia prevention प्रभाव: None None

जनसंख्या: Adults with insomnia or sleep disorders

Key Statistics

8

अध्ययन

40

प्रतिभागी

Positive

B

ग्रेड

Referenced Papers

Digestive diseases (Basel, … 2016 41 उद्धरण
Current signal transduction … 2014 41 उद्धरण
European journal of … 2012 225 उद्धरण

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

सामान्य रूप से उपयोग की जाने वाली खुराकें

sleep:
25-50 mg with B-complex
general:
1.3-1.7 mg/day

अधिकतम सीमा: 100 mg/day (neuropathy risk above)

अनुसंधान में अध्ययन की गई खुराकें

खुराक अवधि प्रभाव N
None -- Positive --
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral -- Positive --
None -- Mixed --
not specified per component 4 weeks Positive 40
None -- Mixed --
None -- Positive --
None -- Positive --
5 mg -- Mixed --

सेवन का सर्वोत्तम समय: Morning or with dinner; high doses before bed may increase dream vividness

Safety & Side Effects

रिपोर्ट किए गए दुष्प्रभाव

  • Nausea
  • Peripheral neuropathy at high doses (>100 mg/day)
  • Vivid dreams
  • Heartburn

ज्ञात अंतःक्रियाएँ

  • Levodopa — B6 may reduce effectiveness (without carbidopa)
  • Phenobarbital and phenytoin — B6 may reduce serum levels
  • Cycloserine — B6 deficiency may worsen side effects

सहनीय अधिकतम सेवन: 100 mg/day (neuropathy risk above)

कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।

Frequently Asked Questions

Does Vitamin B6 help with अनिद्रा?
Based on 8 studies with 40 participants, there is moderate evidence from clinical studies that Vitamin B6 may support अनिद्रा management. Our evidence grade is B (Good Evidence).
How much Vitamin B6 should I take for अनिद्रा?
Studies have used various dosages. A commonly studied range is 25-50 mg with B-complex. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Vitamin B6?
Reported side effects may include Nausea, Peripheral neuropathy at high doses (>100 mg/day), Vivid dreams, Heartburn. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Vitamin B6 and अनिद्रा?
We rate the evidence as Grade B (Good Evidence). This rating is based on 8 peer-reviewed studies with 40 total participants. The overall direction of effect is positive.

Related Evidence

इसके लिए अन्य सामग्री अनिद्रा

Vitamin B6 अन्य स्वास्थ्य स्थितियों के लिए

FDA अस्वीकरण: इन कथनों का Food and Drug Administration द्वारा मूल्यांकन नहीं किया गया है। इस वेबसाइट पर उत्पादों और जानकारी का उद्देश्य किसी बीमारी का निदान, उपचार, इलाज या रोकथाम नहीं है। प्रस्तुत साक्ष्य ग्रेड प्रकाशित पीयर-रिव्यूड अनुसंधान के हमारे विश्लेषण पर आधारित हैं और चिकित्सा सलाह नहीं हैं। कोई भी सप्लीमेंट शुरू करने से पहले हमेशा अपने स्वास्थ्य सेवा प्रदाता से परामर्श करें।