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Ashwagandha لـ الأرق

A

بناءً على 30 دراسة (4 meta-analyses, 5 RCTs) بمشاركة 1,810 مشاركًا إجمالاً. 29/30 دراسة تُظهر تأثيرات إيجابية.

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A

الخلاصة

Ashwagandha is one of the most well-researched herbal supplements for insomnia, with strong and consistent evidence that it may support better sleep quality.

  • 29 out of 30 studies show positive effects, including 5 RCTs and 4 meta-analyses
  • Grade A evidence — the highest level of support among sleep supplements
  • Works through multiple pathways including GABA receptors, histamine modulation, and stress reduction
  • Both healthy adults and people with insomnia have shown improvements in clinical trials

Key Study Findings

Review
The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A …
Dose: None مقابل: None Outcome: None التأثير: None None

المجتمع المدروس: narrative review of ashwagandha clinical trials and basic research (1994-present)

Review
Integrative sleep management: from molecular pathways to conventional and herbal treatments.
Dose: None مقابل: Placebo التأثير: None None
preclinical animal/in vitro study
Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice …
Dose: 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL مقابل: Placebo التأثير: None None
RCT n=90 12 weeks Double-blind
A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep …
Dose: 125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily مقابل: Placebo التأثير: None < 0.05
Meta-analysis n=713 8 weeks Double-blind
The effect of Withania somnifera (Ashwagandha) on mental health symptoms in individuals with mental disorders: …
Dose: 600 mg/day (median) مقابل: Placebo التأثير: SMD=-1.13 (anxiety, outlier-corrected); SMD=-1.28 (depression); SMD=-0.95 (stress); SMD=-1.35 (sleep None
Case Report n=1
Unmasking Potential Withdrawal Effects of Ashwagandha: A Case Report and Review.
Dose: Ashwagandha extract 600 mg/day (prior to discontinuation) مقابل: Placebo التأثير: None None

Key Statistics

31

الدراسات

1810

المشاركون

Positive

A

التقييم

Referenced Papers

Naunyn-Schmiedeberg's archives of … 2025 4 اقتباسات
International journal of … 2023 43 اقتباسات
Child and adolescent … 2023 5 اقتباسات
Pharmacological research 2022 51 اقتباسات
Journal of ethnopharmacology 2020 85 اقتباسات
Phytotherapy research : … 2018 95 اقتباسات
Biological & pharmaceutical … 2014 110 اقتباسات

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

الجرعات الشائعة

sleep:
300-600 mg KSM-66 or Sensoril, before bed

الحد الأعلى: Not established; studied up to 1,200 mg/day

الجرعات المدروسة في الأبحاث

الجرعة المدة التأثير ن
None -- Positive --
None -- Positive --
60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL -- Positive --
125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily 12 weeks Positive 90
600 mg/day (median) 8 weeks Positive 713
Ashwagandha extract 600 mg/day (prior to discontinuation) -- Negative 1
ashwagandha 250 mg/day, ashwagandha 250 mg + tryptophan 175 mg/day, or ashwagandha 600 mg/day (250 m 13 weeks Positive 52
varies across included RCTs -- Positive 254

أفضل وقت للتناول: 1-2 hours before bed

Safety & Side Effects

الآثار الجانبية المُبلّغ عنها

  • Drowsiness
  • GI upset
  • Diarrhea
  • Headache

التفاعلات المعروفة

  • Thyroid medications — ashwagandha may increase thyroid hormone levels
  • Immunosuppressants — ashwagandha may stimulate immune activity
  • Sedatives — potential additive drowsiness
  • Blood sugar medications — may lower blood glucose

الحد الأقصى المسموح به: Not established; studied up to 1,200 mg/day

استشر مقدم الرعاية الصحية دائماً قبل البدء بأي مكمل غذائي.

Frequently Asked Questions

Does Ashwagandha help with الأرق?
Based on 31 studies with 1,810 participants, there is strong evidence from multiple clinical trials that Ashwagandha may support الأرق management. Our evidence grade is A (Strong Evidence).
How much Ashwagandha should I take for الأرق?
Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and الأرق?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 31 peer-reviewed studies with 1,810 total participants. The overall direction of effect is positive.

Related Evidence

إخلاء مسؤولية FDA: لم تُقيَّم هذه البيانات من قبل إدارة الغذاء والدواء (FDA). لا تهدف المنتجات والمعلومات الواردة في هذا الموقع إلى تشخيص أو علاج أو شفاء أو الوقاية من أي مرض. تستند تقييمات الأدلة المعروضة إلى تحليلنا للأبحاث المحكّمة المنشورة ولا تُشكّل نصيحة طبية. استشر مقدم الرعاية الصحية دائماً قبل البدء بأي نظام مكملات.