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Ashwagandha para Insomnio

A

Basado en 30 estudios (4 meta-analyses, 5 RCTs) con 1,810 participantes en total. 29/30 estudios muestran efectos positivos.

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A

Conclusión

Ashwagandha is one of the most well-researched herbal supplements for insomnia, with strong and consistent evidence that it may support better sleep quality.

  • 29 out of 30 studies show positive effects, including 5 RCTs and 4 meta-analyses
  • Grade A evidence — the highest level of support among sleep supplements
  • Works through multiple pathways including GABA receptors, histamine modulation, and stress reduction
  • Both healthy adults and people with insomnia have shown improvements in clinical trials

Key Study Findings

Review
The Clinical Implications of Ashwagandha (Withania somnifera L.) with a Special Reference to Side Effects-A …
Dose: None vs: None Outcome: None Efecto: None None

Población: narrative review of ashwagandha clinical trials and basic research (1994-present)

preclinical animal/in vitro study
Ashwagandha (Withania somnifera (L.) dunal) root extract containing withanolide a alleviates depression-like behavior in mice …
Dose: 60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL vs: Placebo Efecto: None None
RCT n=90 12 weeks Double-blind
A New Ashwagandha Formulation (Zenroot™) Alleviates Stress and Anxiety Symptoms While Improving Mood and Sleep …
Dose: 125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily vs: Placebo Efecto: None < 0.05
Meta-analysis n=713 8 weeks Double-blind
The effect of Withania somnifera (Ashwagandha) on mental health symptoms in individuals with mental disorders: …
Dose: 600 mg/day (median) vs: Placebo Efecto: SMD=-1.13 (anxiety, outlier-corrected); SMD=-1.28 (depression); SMD=-0.95 (stress); SMD=-1.35 (sleep None
Case Report n=1
Unmasking Potential Withdrawal Effects of Ashwagandha: A Case Report and Review.
Dose: Ashwagandha extract 600 mg/day (prior to discontinuation) vs: Placebo Efecto: None None

Key Statistics

31

Estudios

1810

Participantes

Positive

A

Calificación

Referenced Papers

International journal of … 2023 43 citas
Journal of ethnopharmacology 2020 85 citas

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Dosificaciones de uso común

sleep:
300-600 mg KSM-66 or Sensoril, before bed

Límite superior: Not established; studied up to 1,200 mg/day

Dosificaciones estudiadas en la investigación

Dosificación Duración Efecto N
None -- Positive --
None -- Positive --
60 and 100 mg/kg (mice); 100 and 200 µg/mL (HT-22 cells); withanolide A 1.56 and 3.12 µg/mL -- Positive --
125 mg Zenroot (Ashwagandha with 1.5% total withanolides) daily 12 weeks Positive 90
600 mg/day (median) 8 weeks Positive 713
Ashwagandha extract 600 mg/day (prior to discontinuation) -- Negative 1
ashwagandha 250 mg/day, ashwagandha 250 mg + tryptophan 175 mg/day, or ashwagandha 600 mg/day (250 m 13 weeks Positive 52
varies across included RCTs -- Positive 254

Mejor momento para tomar: 1-2 hours before bed

Safety & Side Effects

Efectos secundarios reportados

  • Drowsiness
  • GI upset
  • Diarrhea
  • Headache

Interacciones conocidas

  • Thyroid medications — ashwagandha may increase thyroid hormone levels
  • Immunosuppressants — ashwagandha may stimulate immune activity
  • Sedatives — potential additive drowsiness
  • Blood sugar medications — may lower blood glucose

Ingesta máxima tolerable: Not established; studied up to 1,200 mg/day

Consulte siempre a su profesional de salud antes de comenzar cualquier suplemento.Siempre consulte a su profesional de salud antes de comenzar cualquier suplemento.

Frequently Asked Questions

Does Ashwagandha help with Insomnio?
Based on 31 studies with 1,810 participants, there is strong evidence from multiple clinical trials that Ashwagandha may support Insomnio management. Our evidence grade is A (Strong Evidence).
How much Ashwagandha should I take for Insomnio?
Studies have used various dosages. A commonly studied range is 300-600 mg KSM-66 or Sensoril, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Ashwagandha?
Reported side effects may include Drowsiness, GI upset, Diarrhea, Headache. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Ashwagandha and Insomnio?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 31 peer-reviewed studies with 1,810 total participants. The overall direction of effect is positive.

Related Evidence

Aviso legal FDA: Estas declaraciones no han sido evaluadas por la Food and Drug Administration. Los productos y la información en este sitio web no están destinados a diagnosticar, tratar, curar ni prevenir ninguna enfermedad. Las calificaciones de evidencia presentadas se basan en nuestro análisis de investigación publicada revisada por pares y no constituyen consejo médico. Siempre consulte a su profesional de salud antes de comenzar cualquier régimen de suplementos.