SkullcapSkullcap
herb
别名: Scutellaria lateriflora, American skullcap, Blue skullcap, Mad dog skullcap
About
American skullcap (Scutellaria lateriflora) contains baicalin and scutellarein, flavonoids that bind GABA-A receptors and demonstrate anxiolytic properties. A small double-blind study found it significantly reduced anxiety compared to placebo. Its calming effects may support sleep onset in anxious individuals.
How It Works
Baicalin and scutellarein bind GABA-A receptor benzodiazepine site; flavonoids inhibit glutamate release; antioxidant and anti-inflammatory neuroprotective effects.
Evidence For Conditions
| 健康状况 | 等级 | 研究数量 | 受试者 | |
|---|---|---|---|---|
| 焦虑相关性睡眠问题 | B | 2 | -- | 查看 → |
| Hyperarousal and Cognitive Insomnia | B | 2 | -- | 查看 → |
Side Effects
- Drowsiness (intended effect)
- Rare hepatotoxicity (usually from adulterated products)
- GI discomfort
Drug & Supplement Interactions
- Sedatives and benzodiazepines — additive CNS depression
- Hepatotoxic medications — potential additive liver stress
- Anticonvulsants — may alter seizure threshold
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Related Ingredients
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