Jujube Seed ExtractJujube Seed Extract
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Jujube Seed Extract
Jujube Seed Extract
别名: Suan Zao Ren, Ziziphus jujuba var. spinosa, Ziziphus spinosa
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About
Jujube seed (Ziziphus jujuba var. spinosa) has been used in traditional Chinese medicine as Suan Zao Ren for insomnia for over 2,000 years. Modern research suggests jujuboside A and spinosin, its key compounds, modulate GABAergic and serotonergic neurotransmission to support sedation and anxiolysis.
How It Works
Jujuboside A modulates GABA-A receptor activity; spinosin enhances serotonergic signaling; flavonoids provide anxiolytic effects that reduce pre-sleep arousal.
Evidence For Conditions
Side Effects
- Drowsiness (intended effect)
- Mild GI discomfort
- Vivid dreams (reported anecdotally)
Drug & Supplement Interactions
- Sedatives and benzodiazepines — additive CNS depression
- Anticoagulants — jujube may have mild antiplatelet effects
- CYP450 substrates — potential enzyme inhibition (limited data)
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Related Ingredients
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