褪黑素（Melatonin） 用于 昼夜节律障碍

References

1. [1] Xiaojuan Wang et al.. J AOAC Int. 2026. An HPLC-MS-Based Method for Determination of the D- and L- 5-Methyltetrahydrofolate Isomer Ratio in Dietary Supplements. doi:10.1093/jaoacint/qsaf089 PubMed
2. [2] Ai Terui et al.. PCN Rep. 2026. Correlation between sleep problems and morning serum melatonin and ferritin levels in Japanese 5-year-old children with autism spectrum disorder. doi:10.1002/pcn5.70294 PubMed
3. [3] Haitao Li et al.. Cell Mol Gastroenterol Hepatol. 2026. Disruption of the circadian rhythm induces acute pancreatitis via amino acid metabolism-mediated macrophage infiltration. doi:10.1016/j.jcmgh.2026.101777 PubMed
4. [4] Claudia R C Moreno. Handb Clin Neurol. 2025. Shift work sleep disorder. doi:10.1016/B978-0-323-90918-1.00015-0 PubMed
5. [5] Aleksandar Videnovic et al.. Handb Clin Neurol. 2025. Irregular sleep-wake rhythm disorder: From the pathophysiologic perspective to the treatment. doi:10.1016/B978-0-323-90918-1.00006-X PubMed
6. [6] Shujie Wu et al.. ACS Appl Bio Mater. 2025. Melatonin-Loaded Hydrogel Modulates Circadian Rhythms and Alleviates Oxidative Stress and Inflammation to Promote Wound Healing. doi:10.1021/acsabm.4c01752 PubMed
7. [7] Kacper Żełabowski et al.. Molecules. 2025. The Efficacy of Melatonergic Receptor Agonists Used in Clinical Practice in Insomnia Treatment: Melatonin, Tasimelteon, Ramelteon, Agomelatine, and Selected Herbs. doi:10.3390/molecules30183814 PubMed
8. [8] Siqi Wang et al.. NPJ Sci Food. 2025. Revealing the mechanism of Ganoderma lucidum insoluble dietary fiber alleviating NAFLD through transcriptomics and metabolomics. doi:10.1038/s41538-025-00586-6 PubMed
9. [9] Naoise C Synnott et al.. PLoS One. 2025. Melatonin agonist tasimelteon (HETLIOZ®) improves sleep in patients with primary insomnia: A multicenter, randomized, double-blind, placebo-controlled trial. doi:10.1371/journal.pone.0332366 PubMed
10. [10] Keith A Barnes. JAAPA. 2025. Delayed sleep-wake phase disorder. doi:10.1097/01.JAA.0000000000000096 PubMed
11. [11] Brandon Luu et al.. Front Psychiatry. 2025. ADHD as a circadian rhythm disorder: evidence and implications for chronotherapy. doi:10.3389/fpsyt.2025.1697900 PubMed
12. [12] Mahide Muge Yilmaz Topcam et al.. Foods. 2025. Exogenous L-Cysteine and Its Transport Through CtaP Play a Role in Biofilm Formation, Swimming Motility, and Swarming Motility of Listeria … doi:10.3390/foods14111845 PubMed
13. [13] Tatiana Palotta Minari et al.. Sleep Breath. 2025. Unraveling the connection between the Mediterranean diet and sleep health: from biological mechanisms to clinical implications. doi:10.1007/s11325-025-03546-2 PubMed
14. [14] Giulia Pisanò et al.. Sleep Med. 2025. A novel CSNK1Dvariant in pediatric advanced sleep-wake phase syndrome. doi:10.1016/j.sleep.2025.106524 PubMed
15. [15] Dongliang Shi et al.. Medicine (Baltimore). 2025. Identifying potential mechanisms of circadian rhythm-related gene marker prognosis, immune infiltration, and melatonin intervention in thyroid cancer based on bioinformatics … doi:10.1097/MD.0000000000045486 PubMed
16. [16] Rebecca L Kelley et al.. Hum Reprod. 2025. A prospective randomized controlled trial of antioxidants in human IVF and embryo culture media. doi:10.1093/humrep/deaf183 PubMed
17. [17] Stefano Comai et al.. J Pineal Res. 2024. Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views. doi:10.1111/jpi.13011 PubMed
18. [18] Muhammad Saeed et al.. Poult Sci. 2024. Molecular strategies to enhance the keratinase gene expression and its potential implications in poultry feed industry. doi:10.1016/j.psj.2024.103606 PubMed
19. [19] Junsoo Chung et al.. Clin Psychopharmacol Neurosci. 2024. Bipolar Disorder, Circadian Rhythm and Clock Genes. doi:10.9758/cpn.23.1093 PubMed
20. [20] Bhavya Narala et al.. Curr Opin Pediatr. 2024. Delayed sleep wake phase disorder in adolescents: an updated review. doi:10.1097/MOP.0000000000001322 PubMed
21. [21] Marcela de Paiva Foletto-Felipe et al.. Plant Physiol Biochem. 2024. Inhibition of sulfur assimilation by S-benzyl-L-cysteine: Impacts on growth, photosynthesis, and leaf proteome of maize plants. doi:10.1016/j.plaphy.2024.109173 PubMed
22. [22] Antonio Del Casale et al.. Minerva Med. 2024. The use of prolonged-release melatonin in circadian medicine: a systematic review. doi:10.23736/S0026-4806.24.09303-0 PubMed
23. [23] Julio Baudin et al.. Biomed Pharmacother. 2024. A cocktail of histidine, carnosine, cysteine and serine reduces adiposity and improves metabolic health and adipose tissue immunometabolic function in … doi:10.1016/j.biopha.2024.117326 PubMed
24. [24] Hui Yang et al.. Biotechnol J. 2024. Synergistic application of atmospheric and room temperature plasma mutagenesis and adaptive laboratory evolution improves the tolerance of Escherichia coli to … doi:10.1002/biot.202300648 PubMed
25. [25] Sonia Gago et al.. Reprod Domest Anim. 2024. Impact of N-acetyl-L-cysteine on spindle morphology and reactive oxygen species in vitrified/warmed in vitro matured bovine oocytes. doi:10.1111/rda.14619 PubMed
26. [26] Concepcion Sanchez et al.. Res Sq. 2024. Sustained xanthine oxidase inhibitor treat to target urate lowering therapy rewires a tight inflammation serum protein interactome. doi:10.21203/rs.3.rs-3770277/v1 PubMed
27. [27] Julie Garrivet et al.. J Clin Sleep Med. 2024. Images: "Too much heat for my non-24-hour sleep-wake disorder!" A case report. doi:10.5664/jcsm.10858 PubMed
28. [28] O Hecmarie Meléndez-Fernández et al.. Int J Mol Sci. 2023. Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism. doi:10.3390/ijms24043392 PubMed
29. [29] Colin Tuft et al.. Clin Interv Aging. 2023. Current Insights into the Risks of Using Melatonin as a Treatment for Sleep Disorders in Older Adults. doi:10.2147/CIA.S361519 PubMed
30. [30] Francy Cruz-Sanabria et al.. Curr Neuropharmacol. 2023. Melatonin as a Chronobiotic with Sleep-promoting Properties. doi:10.2174/1570159X20666220217152617 PubMed
31. [31] Tian-Ji Xia et al.. Front Pharmacol. 2023. Melatonin-related dysfunction in chronic restraint stress triggers sleep disorders in mice. doi:10.3389/fphar.2023.1210393 PubMed
32. [32] Meenakshi Pundir et al.. Anal Chim Acta. 2023. Colorimetric sensing assay based on aptamer-gold nanoparticles for rapid detection of salivary melatonin to monitor circadian rhythm sleep disorders. doi:10.1016/j.aca.2023.341777 PubMed
33. [33] Craig Gouldthorpe et al.. Front Oncol. 2023. Circadian rhythm disorders in patients with advanced cancer: a scoping review. doi:10.3389/fonc.2023.1240284 PubMed
34. [34] Yavuz Selim Atan et al.. Turk J Ophthalmol. 2023. The Effect of Blindness on Biological Rhythms and the Consequences of Circadian Rhythm Disorder. doi:10.4274/tjo.galenos.2022.59296 PubMed
35. [35] Hui Yang et al.. J Pineal Res. 2023. RP58 knockdown contributes to hypoxia-ischemia-induced pineal dysfunction and circadian rhythm disruption in neonatal rats. doi:10.1111/jpi.12885 PubMed
36. [36] Alessandra Giordano et al.. J Clin Neurophysiol. 2023. Objective Diagnosis of Circadian Rhythm Disorders. doi:10.1097/WNP.0000000000000951 PubMed
37. [37] Alexandra Wu. Sleep Biol Rhythms. 2023. Updates and confounding factors in delayed sleep-wake phase disorder. doi:10.1007/s41105-023-00454-4 PubMed
38. [38] Nijee S Luthra et al.. Front Neurosci. 2023. Targeting neuroendocrine abnormalities in Parkinson's disease with exercise. doi:10.3389/fnins.2023.1228444 PubMed
39. [39] H Pertiwi et al.. Br Poult Sci. 2023. N-acetyl-L-cysteine improves the performance of chronic cyclic heat-stressed finisher broilers but has no effect on tissue glutathione levels. doi:10.1080/00071668.2023.2264234 PubMed
40. [40] Irma M Vlasac et al.. Sleep. 2023. A Novel Home-Based Study of Circadian Rhythms: Design, Rationale, and Methods for the Circadia Study. doi:10.1093/sleep/zsad197 PubMed
41. [41] Xiao-Qian Chen et al.. Front Public Health. 2023. Prevalence and risk factors of sub-health and circadian rhythm disorder of cortisol, melatonin, and temperature among Chinese midwives. doi:10.3389/fpubh.2023.1142995 PubMed
42. [42] J J Poza et al.. Neurologia (Engl Ed). 2022. Melatonin in sleep disorders. doi:10.1016/j.nrl.2018.08.002 PubMed
43. [43] Saptadip Samanta. Arch Physiol Biochem. 2022. Physiological and pharmacological perspectives of melatonin. doi:10.1080/13813455.2020.1770799 PubMed
44. [44] J J Poza et al.. Neurologia (Engl Ed). 2022. Melatonin in sleep disorders. doi:10.1016/j.nrleng.2018.08.004 PubMed
45. [45] Shi-Yu Sun et al.. Curr Neuropharmacol. 2022. Treatment of Circadian Rhythm Sleep-Wake Disorders. doi:10.2174/1570159X19666210907122933 PubMed
46. [46] Niall M McGowan et al.. CNS Drugs. 2022. Hypnotic and Melatonin/Melatonin-Receptor Agonist Treatment in Bipolar Disorder: A Systematic Review and Meta-Analysis. doi:10.1007/s40263-022-00911-7 PubMed
47. [47] Bárbara Carriedo-Diez et al.. Int J Environ Res Public Health. 2022. The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review. doi:10.3390/ijerph191610199 PubMed
48. [48] Tsung-Yu Lee et al.. Poult Sci. 2022. Bacillus amyloliquefaciens CU33 fermented feather meal-soybean meal product improves the intestinal morphology to promote the growth performance of broilers. doi:10.1016/j.psj.2022.102027 PubMed
49. [49] Xue-Lei Yin et al.. Exp Neurol. 2022. Melatonin pretreatment prevents propofol-induced sleep disturbance by modulating circadian rhythm in rats. doi:10.1016/j.expneurol.2022.114086 PubMed
50. [50] Arpita Shah et al.. Metab Syndr Relat Disord. 2022. Is Shift Work Sleep Disorder a Risk Factor for Metabolic Syndrome and Its Components? A Systematic Review of Cross-Sectional Studies. doi:10.1089/met.2021.0070 PubMed
51. [51] Feifei Shi et al.. Environ Pollut. 2022. Exogenous melatonin protects preimplantation embryo development from decabromodiphenyl ethane-induced circadian rhythm disorder and endogenous melatonin reduction. doi:10.1016/j.envpol.2021.118445 PubMed
52. [52] Xu He et al.. J Pineal Res. 2022. Sini powder with paroxetine ameliorates major depressive disorder by modulating circadian rhythm: A randomized, double-blind, placebo-controlled trial. doi:10.1111/jpi.12832 PubMed
53. [53] A Gupta et al.. Lett Appl Microbiol. 2022. Culture media, DMSO and efflux affect the antibacterial activity of cisplatin and oxaliplatin. doi:10.1111/lam.13767 PubMed
54. [54] Na Pan et al.. Sci Total Environ. 2022. Inhibitory effects of zinc chloride (ZnCl2), n-acetyl-L-cysteine (NAC), and calcium/calmodulin dependent protein kinase II inhibitor (KN93) on Cd2+-induced abnormal cell … doi:10.1016/j.scitotenv.2022.155208 PubMed
55. [55] Yulin Sun et al.. BMJ Open. 2022. Melatonin supplementation for the treatment of infantile spasms: protocol for a randomised placebo-controlled triple-blind trial. doi:10.1136/bmjopen-2021-057970 PubMed
56. [56] Maxim D Malyshev et al.. Soft Matter. 2022. Self-assembly in systems based on L-cysteine-silver-nitrate aqueous solution: multiscale computer simulation. doi:10.1039/d2sm00846g PubMed
57. [57] Jingwen Li et al.. NPJ Parkinsons Dis. 2022. Melatonin ameliorates Parkinson's disease via regulating microglia polarization in a RORα-dependent pathway. doi:10.1038/s41531-022-00352-5 PubMed
58. [58] Qinggong Wang et al.. Nat Commun. 2022. Structural basis of the ligand binding and signaling mechanism of melatonin receptors. doi:10.1038/s41467-022-28111-3 PubMed
59. [59] Tyler A Steele et al.. Neurotherapeutics. 2021. Circadian Rhythm Sleep-Wake Disorders: a Contemporary Review of Neurobiology, Treatment, and Dysregulation in Neurodegenerative Disease. doi:10.1007/s13311-021-01031-8 PubMed
60. [60] Landon Hester et al.. Chronobiol Int. 2021. Evening wear of blue-blocking glasses for sleep and mood disorders: a systematic review. doi:10.1080/07420528.2021.1930029 PubMed
61. [61] Lijie Zhou et al.. Clin Transl Med. 2021. Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1. doi:10.1002/ctm2.449 PubMed
62. [62] Eva Hadadi et al.. Endocr Relat Cancer. 2021. Role of circadian rhythm disorders on EMT and tumour-immune interactions in endocrine-related cancers. doi:10.1530/ERC-20-0390 PubMed
63. [63] Sophie Morin et al.. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. Biological action of docosahexaenoic acid in a 3D tissue-engineered psoriatic skin model: Focus on the PPAR signaling pathway. doi:10.1016/j.bbalip.2021.159032 PubMed
64. [64] Xiaoli Wu et al.. Front Neurol. 2021. Circadian Rhythm Disorders and Corresponding Functional Brain Abnormalities in Young Female Nurses: A Preliminary Study. doi:10.3389/fneur.2021.664610 PubMed
65. [65] B Ogunlade et al.. Food Chem Toxicol. 2021. Neurotherapeutic and antioxidant response of D-ribose-L-Cysteine nutritional dietary supplements on Alzheimer-type hippocampal neurodegeneration induced by cuprizone in adult male wistar … doi:10.1016/j.fct.2020.111862 PubMed
66. [66] Gabriel O Oludare et al.. J Basic Clin Physiol Pharmacol. 2021. Potential anti-toxic effect of d-ribose-l-cysteine supplement on the reproductive functions of male rats administered cyclophosphamide. doi:10.1515/jbcpp-2020-0267 PubMed
67. [67] Ning Sha et al.. Neural Regen Res. 2021. The role of pineal microRNA-325 in regulating circadian rhythms after neonatal hypoxic-ischemic brain damage. doi:10.4103/1673-5374.308101 PubMed
68. [68] Emine Mulayim et al.. Arch Med Res. 2021. Melatonin Receptor Gene Polymorphism in Bipolar-I Disorder. doi:10.1016/j.arcmed.2021.01.002 PubMed
69. [69] Ran Meng et al.. Ann Palliat Med. 2021. Effects of circadian rhythm disorder on body composition in women aged 31-40 years. doi:10.21037/apm-20-2267 PubMed
70. [70] Attia Ahmad et al.. Curr Top Behav Neurosci. 2021. Sleep and Circadian Rhythm Disorder in Bipolar Affective Disorder. doi:10.1007/7854_2020_150 PubMed
71. [71] P Proserpio et al.. Climacteric. 2020. Insomnia and menopause: a narrative review on mechanisms and treatments. doi:10.1080/13697137.2020.1799973 PubMed
72. [72] José Rafael P Zuzuárregui et al.. Neurotherapeutics. 2020. Sleep Issues in Parkinson's Disease and Their Management. doi:10.1007/s13311-020-00938-y PubMed
73. [73] Katarzyna Lewandowska et al.. Sleep Med. 2020. The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit … doi:10.1016/j.sleep.2020.01.019 PubMed
74. [74] Sushil K Jain et al.. J Am Coll Nutr. 2020. Can Vitamin D and L-Cysteine Co-Supplementation Reduce 25(OH)-Vitamin D Deficiency and the Mortality Associated with COVID-19 in African Americans? doi:10.1080/07315724.2020.1789518 PubMed
75. [75] Lauren Ciulla et al.. J Glaucoma. 2020. Circadian Rhythm and Glaucoma: What do We Know? doi:10.1097/IJG.0000000000001402 PubMed
76. [76] Luigi Ferini-Strambi et al.. Curr Treat Options Neurol. 2020. Therapy for Insomnia and Circadian Rhythm Disorder in Alzheimer Disease. doi:10.1007/s11940-020-0612-z PubMed
77. [77] Fengqi Yang et al.. Foods. 2020. Effect of L-cysteine, Boswellia serrata, and Whey Protein on the Antioxidant and Physicochemical Properties of Pork Patties. doi:10.3390/foods9080993 PubMed
78. [78] Feifei Zhang et al.. Hum Brain Mapp. 2020. The effect of jet lag on the human brain: A neuroimaging study. doi:10.1002/hbm.24945 PubMed
79. [79] Lucia Pucciarini et al.. J Pharm Biomed Anal. 2020. Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplement. doi:10.1016/j.jpba.2019.113066 PubMed
80. [80] Julia Ribeiro da Silva Vallim et al.. Sleep Med. 2020. Sleep parameters assessed by actigraphy in Fabry's disease patients: a proof-of-concept. doi:10.1016/j.sleep.2020.01.012 PubMed
81. [81] Terumi Ayuse et al.. Medicine (Baltimore). 2020. Study on the preventive effect of ramelteon on the onset of sleep disorder after general anesthesia in patients with autism … doi:10.1097/MD.0000000000022826 PubMed
82. [82] Elise R Facer-Childs et al.. Sleep Med. 2019. Resetting the late timing of 'night owls' has a positive impact on mental health and performance. doi:10.1016/j.sleep.2019.05.001 PubMed
83. [83] Jade M Murray et al.. Sleep Med. 2019. Sleep regularity is associated with sleep-wake and circadian timing, and mediates daytime function in Delayed Sleep-Wake Phase Disorder. doi:10.1016/j.sleep.2019.03.009 PubMed
84. [84] David Landzberg et al.. Curr Sleep Med Rep. 2019. Is Idiopathic Hypersomnia a Circadian Rhythm Disorder? doi:10.1007/s40675-019-00154-x PubMed
85. [85] Julia Ribeiro da Silva Vallim et al.. Chronobiol Int. 2019. Rhythmic changes in Fabry disease: Inversion and non-oscillatory pattern in 6-sulfatoxymelatonin daily profile. doi:10.1080/07420528.2018.1560308 PubMed
86. [86] Argelinda Baroni. J Am Acad Child Adolesc Psychiatry. 2019. Teens Who Can't Sleep: Insomnia or Circadian Rhythm Disorder? doi:10.1016/j.jaac.2018.11.010 PubMed
87. [87] Melanie Pogach et al.. Neurol Clin. 2019. Challenging Circadian Rhythm Disorder Cases. doi:10.1016/j.ncl.2019.04.001 PubMed
88. [88] Nava Zisapel. Br J Pharmacol. 2018. New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. doi:10.1111/bph.14116 PubMed
89. [89] Lauren A Watson et al.. J Physiol. 2018. Increased sensitivity of the circadian system to light in delayed sleep-wake phase disorder. doi:10.1113/JP275917 PubMed
90. [90] Sarah Hartley et al.. Curr Neurol Neurosci Rep. 2018. Circadian Rhythm Disturbances in the Blind. doi:10.1007/s11910-018-0876-9 PubMed
91. [91] Takafumi Fukuda et al.. Chronobiol Int. 2018. A randomized, double-blind and placebo-controlled crossover trial on the effect of l-ornithine ingestion on the human circadian clock. doi:10.1080/07420528.2018.1490315 PubMed
92. [92] Sumera Shaikh Solaiman et al.. J Clin Sleep Med. 2018. Non-24-Hour Sleep-Wake Circadian Rhythm Disorder in a Sighted Male With Normal Functioning. doi:10.5664/jcsm.7008 PubMed
93. [93] Bhavesh Trikamji et al.. Cureus. 2018. Recurrent Chemical Meningitis Due to Parasellar Epidermoid Cyst. doi:10.7759/cureus.3496 PubMed
94. [94] Dieter Riemann et al.. J Sleep Res. 2017. European guideline for the diagnosis and treatment of insomnia. doi:10.1111/jsr.12594 PubMed
95. [95] Sophie M T Wehrens et al.. Curr Biol. 2017. Meal Timing Regulates the Human Circadian System. doi:10.1016/j.cub.2017.04.059 PubMed
96. [96] Zizhen Xie et al.. Neurol Res. 2017. A review of sleep disorders and melatonin. doi:10.1080/01616412.2017.1315864 PubMed
97. [97] Lauren A E Erland et al.. J Clin Sleep Med. 2017. Melatonin Natural Health Products and Supplements: Presence of Serotonin and Significant Variability of Melatonin Content. doi:10.5664/jcsm.6462 PubMed
98. [98] Milena Pavlova. Continuum (Minneap Minn). 2017. Circadian Rhythm Sleep-Wake Disorders. doi:10.1212/CON.0000000000000499 PubMed
99. [99] Amy W Amara et al.. Curr Treat Options Neurol. 2017. Treatment of Sleep Dysfunction in Parkinson's Disease. doi:10.1007/s11940-017-0461-6 PubMed
100. [100] Deetje Iggena et al.. J Pineal Res. 2017. Melatonin restores hippocampal neural precursor cell proliferation and prevents cognitive deficits induced by jet lag simulation in adult mice. doi:10.1111/jpi.12397 PubMed
101. [101] Jonathan S Emens et al.. Drugs. 2017. Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind. doi:10.1007/s40265-017-0707-3 PubMed
102. [102] Deepa Burman. FP Essent. 2017. Sleep Disorders: Circadian Rhythm Sleep-Wake Disorders. PubMed
103. [103] Mervyn J Merrilees et al.. J Tissue Eng Regen Med. 2017. Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin. doi:10.1002/term.1913 PubMed
104. [104] Iga Hołyńska-Iwan et al.. Pol Merkur Lekarski. 2017. [The application of N-acetylcysteine in optimization of specific pharmacological therapies]. PubMed
105. [105] Jiabei Liu et al.. Annu Rev Pharmacol Toxicol. 2016. MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective. doi:10.1146/annurev-pharmtox-010814-124742 PubMed
106. [106] Yvan Touitou et al.. J Physiol Paris. 2016. Disruption of adolescents' circadian clock: The vicious circle of media use, exposure to light at night, sleep loss and risk … doi:10.1016/j.jphysparis.2017.05.001 PubMed
107. [107] Ze he Song et al.. Innate Immun. 2016. L-cysteine protects intestinal integrity, attenuates intestinal inflammation and oxidant stress, and modulates NF-κB and Nrf2 pathways in weaned piglets after … doi:10.1177/1753425916632303 PubMed
108. [108] Thomas A Hogerheyde et al.. Stem Cells Int. 2016. Optimization of Corneal Epithelial Progenitor Cell Growth on Bombyx mori Silk Fibroin Membranes. doi:10.1155/2016/8310127 PubMed
109. [109] Frances M Wolber et al.. Nutrients. 2016. Cysteic Acid in Dietary Keratin is Metabolized to Glutathione and Liver Taurine in a Rat Model of Human Digestion. doi:10.3390/nu8020104 PubMed
110. [110] Masatake Kurita et al.. Neuropsychiatr Dis Treat. 2016. Non-24-hour sleep-wake syndrome improved by low-dose valproic acid: a case report. doi:10.2147/NDT.S115648 PubMed
111. [111] Zhe Qu et al.. Neuromolecular Med. 2016. Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration. doi:10.1007/s12017-016-8410-1 PubMed
112. [112] Steven W Lockley et al.. Lancet. 2015. Tasimelteon for non-24-hour sleep-wake disorder in totally blind people (SET and RESET): two multicentre, randomised, double-masked, placebo-controlled phase 3 trials. doi:10.1016/S0140-6736(15)60031-9 PubMed
113. [113] Kathryn J Reid et al.. Sleep Med Clin. 2015. Jet Lag and Shift Work Disorder. doi:10.1016/j.jsmc.2015.08.006 PubMed
114. [114] Makoto Uchiyama et al.. Sleep Med Clin. 2015. Non-24-Hour Sleep-Wake Rhythm Disorder in Sighted and Blind Patients. doi:10.1016/j.jsmc.2015.07.006 PubMed
115. [115] Sabra M Abbott et al.. Sleep Med Clin. 2015. Irregular Sleep-Wake Rhythm Disorder. doi:10.1016/j.jsmc.2015.08.005 PubMed
116. [116] D N Neubauer. Drugs Today (Barc). 2015. Tasimelteon for the treatment of non-24-hour sleep-wake disorder. doi:10.1358/dot.2015.51.1.2258364 PubMed
117. [117] Francisco Tortorolo et al.. Medwave. 2015. Is melatonin useful for jet lag? doi:10.5867/medwave.2015.6343 PubMed
118. [118] Anna Wojciechowska et al.. Reprod Biol. 2015. Short-term incubation of bovine placentome sections as a tool to study xenobiotic mechanism of action. doi:10.1016/j.repbio.2015.10.002 PubMed
119. [119] Dokyung Lee et al.. Sleep Med. 2015. Forced entrainment by using light therapy, modafinil and melatonin in a sighted patient with non-24-hour sleep-wake disorder. doi:10.1016/j.sleep.2014.09.020 PubMed
120. [120] Hirokuni Tagaya et al.. Nihon Rinsho. 2015. [Circadian rhythm sleep-wake disorder (circadian rhythm sleep disorder)]. PubMed
121. [121] Erin E Flynn-Evans et al.. J Biol Rhythms. 2014. Circadian Rhythm Disorders and Melatonin Production in 127 Blind Women with and without Light Perception. doi:10.1177/0748730414536852 PubMed
122. [122] Lourdes M DelRosso et al.. J Clin Sleep Med. 2014. Sleep-wake pattern following gunshot suprachiasmatic damage. doi:10.5664/jcsm.3628 PubMed
123. [123] Mariko Yanagihara et al.. Tohoku J Exp Med. 2014. The melatonin receptor agonist is effective for free-running type circadian rhythm sleep disorder: case report on two sighted patients. doi:10.1620/tjem.234.123 PubMed
124. [124] Stephen M Stahl. CNS Spectr. 2014. Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients. doi:10.1017/S1092852914000637 PubMed
125. [125] Ichiya Sano et al.. Jpn J Ophthalmol. 2014. Estimation of the melatonin suppression index through clear and yellow-tinted intraocular lenses. doi:10.1007/s10384-014-0320-x PubMed
126. [126] Shinsuke Yoshihara et al.. Seishin Shinkeigaku Zasshi. 2014. [Effects of ramelteon on a patient with circadian rhythm sleep disorder and mood disorder]. PubMed
127. [127] Samuele Cortese et al.. J Am Acad Child Adolesc Psychiatry. 2013. Assessment and management of sleep problems in youths with attention-deficit/hyperactivity disorder. doi:10.1016/j.jaac.2013.06.001 PubMed
128. [128] Phyllis C Zee et al.. Continuum (Minneap Minn). 2013. Circadian rhythm abnormalities. doi:10.1212/01.CON.0000427209.21177.aa PubMed
129. [129] Prasenjit Manna et al.. J Cell Biochem. 2013. L-cysteine and hydrogen sulfide increase PIP3 and AMPK/PPARγ expression and decrease ROS and vascular inflammation markers in high glucose treated … doi:10.1002/jcb.24578 PubMed
130. [130] Ane Wilhelmsen-Langeland et al.. J Biol Rhythms. 2013. A randomized controlled trial with bright light and melatonin for the treatment of delayed sleep phase disorder: effects on subjective … doi:10.1177/0748730413500126 PubMed
131. [131] Delwyn J Bartlett et al.. Med J Aust. 2013. Circadian rhythm disorders among adolescents: assessment and treatment options. doi:10.5694/mja13.10912 PubMed
132. [132] Shingo Kitamura et al.. Biol Psychiatry. 2013. Intrinsic circadian period of sighted patients with circadian rhythm sleep disorder, free-running type. doi:10.1016/j.biopsych.2012.06.027 PubMed
133. [133] Kazuo Mishima. Nihon Rinsho. 2013. [Circadian rhythm sleep disorder]. PubMed
134. [134] Ana Adan et al.. Chronobiol Int. 2012. Circadian typology: a comprehensive review. doi:10.3109/07420528.2012.719971 PubMed
135. [135] Makoto Bannai et al.. Front Neurol. 2012. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. doi:10.3389/fneur.2012.00061 PubMed
136. [136] Irina V Zhdanova et al.. PLoS One. 2012. Familial circadian rhythm disorder in the diurnal primate, Macaca mulatta. doi:10.1371/journal.pone.0033327 PubMed
137. [137] Andrew D Krystal et al.. J Clin Psychiatry. 2012. Shift work disorder case studies: applying management principles in clinical practice. doi:10.4088/JCP.11073br4 PubMed
138. [138] Joshua Hogins et al.. PLoS One. 2011. Excitotoxicity triggered by Neurobasal culture medium. doi:10.1371/journal.pone.0025633 PubMed
139. [139] Rachel E Fargason et al.. Psychopharmacol Bull. 2011. Ramelteon for Insomnia Related to Attention-Deficit/Hyperactivity Disorder (ADHD). doi:10.64719/pb.4063 PubMed
140. [140] Mark A Brown et al.. J Clin Sleep Med. 2011. Circadian rhythm sleep disorder, free-running type in a sighted male with severe depression, anxiety, and agoraphobia. PubMed
141. [141] Michael Thorpy. Postgrad Med. 2011. Understanding and diagnosing shift work disorder. doi:10.3810/pgm.2011.09.2464 PubMed
142. [142] Karuna Dewan et al.. Sleep. 2011. Light-induced changes of the circadian clock of humans: increasing duration is more effective than increasing light intensity. doi:10.1093/sleep/34.5.593 PubMed
143. [143] Venkatramanujam Srinivasan et al.. Adv Ther. 2010. Jet lag, circadian rhythm sleep disturbances, and depression: the role of melatonin and its analogs. doi:10.1007/s12325-010-0065-y PubMed
144. [144] Sally A Ferguson et al.. Expert Rev Neurother. 2010. Melatonin agonists and insomnia. doi:10.1586/ern.10.1 PubMed
145. [145] A M Mazotto et al.. Lett Appl Microbiol. 2010. Keratinolytic activity of Bacillus subtilis AMR using human hair. doi:10.1111/j.1472-765X.2009.02760.x PubMed
146. [146] Emiliano Ricardo Vasconcelos Rios et al.. Int J Neurosci. 2010. Melatonin: pharmacological aspects and clinical trends. doi:10.3109/00207454.2010.492921 PubMed
147. [147] A Abbas et al.. J R Coll Physicians Edinb. 2010. A circadian rhythm sleep disorder: melatonin resets the biological clock. doi:10.4997/JRCPE.2010.406 PubMed
148. [148] David H Baker. Amino Acids. 2009. Advances in protein-amino acid nutrition of poultry. doi:10.1007/s00726-008-0198-3 PubMed
149. [149] N Ahmad Aziz et al.. J Neurol. 2009. Delayed onset of the diurnal melatonin rise in patients with Huntington's disease. doi:10.1007/s00415-009-5196-1 PubMed
150. [150] Robert L Sack. Travel Med Infect Dis. 2009. The pathophysiology of jet lag. doi:10.1016/j.tmaid.2009.01.006 PubMed
151. [151] Kathryn J Reid et al.. Semin Neurol. 2009. Circadian rhythm disorders. doi:10.1055/s-0029-1237120 PubMed
152. [152] Ståle Pallesen et al.. Tidsskr Nor Laegeforen. 2009. [Circadian rhythm sleep disorders]. doi:10.4045/tidsskr.08.0226 PubMed
153. [153] Anne-Marie Chang et al.. J Biol Rhythms. 2009. Sleep timing and circadian phase in delayed sleep phase syndrome. doi:10.1177/0748730409339611 PubMed
154. [154] Oscar Jerónimo Simón Padilla et al.. Rev Esp Geriatr Gerontol. 2009. [Use of combined treatment with melatonin and clomethiazole in circadian rhythm sleep disorder in the elderly with dementia]. doi:10.1016/j.regg.2009.03.015 PubMed
155. [155] Feride Gökben Hizli et al.. Turk Psikiyatri Derg. 2009. [Delayed sleep phase type sleep disorder and chronotherapy]. PubMed
156. [156] Rüdiger Hardeland. Curr Opin Investig Drugs. 2009. Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders. PubMed
157. [157] Seithikurippu R Pandi-Perumal et al.. Nat Clin Pract Neurol. 2008. The roles of melatonin and light in the pathophysiology and treatment of circadian rhythm sleep disorders. doi:10.1038/ncpneuro0847 PubMed
158. [158] Rüdiger Hardeland et al.. Arzneimittelforschung. 2008. Melatonergic drugs in clinical practice. doi:10.1055/s-0031-1296459 PubMed
159. [159] Venkataramanujan Srinivasan et al.. Travel Med Infect Dis. 2008. Jet lag: therapeutic use of melatonin and possible application of melatonin analogs. doi:10.1016/j.tmaid.2007.12.002 PubMed
160. [160] Ana Barion et al.. Sleep Med. 2007. A clinical approach to circadian rhythm sleep disorders. doi:10.1016/j.sleep.2006.11.017 PubMed
161. [161] Ramez Wassef et al.. J Neurosci. 2007. Methionine sulfoxide reductase A and a dietary supplement S-methyl-L-cysteine prevent Parkinson's-like symptoms. doi:10.1523/JNEUROSCI.0322-07.2007 PubMed
162. [162] Ryan N Dilger et al.. J Nutr. 2007. Excess dietary L-cysteine, but not L-cystine, is lethal for chicks but not for rats or pigs. doi:10.1093/jn/137.2.331 PubMed
163. [163] Theodore Parthimos et al.. Clin Chem Lab Med. 2007. L-cysteine supplementation prevents exercise-induced alterations in human erythrocyte membrane acetylcholinesterase and Na+,K+-ATPase activities. doi:10.1515/CCLM.2007.005 PubMed
164. [164] Leon C Lack et al.. Behav Sleep Med. 2007. Clinical management of delayed sleep phase disorder. doi:10.1207/s15402010bsm0501_4 PubMed
165. [165] Timothy I Morgenthaler et al.. Sleep. 2007. Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. doi:10.1093/sleep/30.11.1445 PubMed
166. [166] Robert L Sack et al.. Sleep. 2007. Circadian rhythm sleep disorders: part I, basic principles, shift work and jet lag disorders. An American Academy of Sleep Medicine … doi:10.1093/sleep/30.11.1460 PubMed
167. [167] S R Pandi-Perumal et al.. FEBS J. 2006. Melatonin: Nature's most versatile biological signal? doi:10.1111/j.1742-4658.2006.05322.x PubMed
168. [168] Hélène De Leersnyder et al.. Mol Cell Endocrinol. 2006. Circadian rhythm disorder in a rare disease: Smith-Magenis syndrome. doi:10.1016/j.mce.2006.03.043 PubMed
169. [169] Lin Ji et al.. Tissue Eng. 2006. Generation and differentiation of human embryonic stem cell-derived keratinocyte precursors. doi:10.1089/ten.2006.12.665 PubMed
170. [170] Dong-Youn Lee et al.. J Dermatol Sci. 2006. A new dermal equivalent: the use of dermal fibroblast culture alone without exogenous materials. doi:10.1016/j.jdermsci.2006.03.007 PubMed
171. [171] Josephine Arendt. J Biol Rhythms. 2005. Melatonin: characteristics, concerns, and prospects. doi:10.1177/0748730405277492 PubMed
172. [172] Kristiaan B Van der Heijden et al.. Chronobiol Int. 2005. Idiopathic chronic sleep onset insomnia in attention-deficit/hyperactivity disorder: a circadian rhythm sleep disorder. doi:10.1081/CBI-200062410 PubMed
173. [173] Gary S Richardson. J Clin Psychiatry. 2005. The human circadian system in normal and disordered sleep. PubMed
174. [174] J T Doljansky et al.. Chronobiol Int. 2005. Working under daylight intensity lamp: an occupational risk for developing circadian rhythm sleep disorder? doi:10.1081/CBI-200062422 PubMed
175. [175] Bihui Zhong et al.. J Cell Sci. 2004. Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation. doi:10.1242/jcs.01016 PubMed
176. [176] Kathryn J Reid et al.. Semin Neurol. 2004. Circadian rhythm disorders. doi:10.1055/s-2004-835063 PubMed
177. [177] Fred W Turek et al.. Sleep Med. 2004. Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists. doi:10.1016/j.sleep.2004.07.009 PubMed
178. [178] C Cajochen et al.. J Neuroendocrinol. 2003. Role of melatonin in the regulation of human circadian rhythms and sleep. doi:10.1046/j.1365-2826.2003.00989.x PubMed
179. [179] Russel J Reiter. Best Pract Res Clin Endocrinol Metab. 2003. Melatonin: clinical relevance. doi:10.1016/s1521-690x(03)00016-2 PubMed
180. [180] N Morley et al.. J Photochem Photobiol B. 2003. N-acetyl-L-cysteine prevents DNA damage induced by UVA, UVB and visible radiation in human fibroblasts. doi:10.1016/j.jphotobiol.2003.06.004 PubMed
181. [181] A Herxheimer et al.. Cochrane Database Syst Rev. 2002. Melatonin for the prevention and treatment of jet lag. doi:10.1002/14651858.CD001520 PubMed
182. [182] M Rufo-Campos. Rev Neurol. 2002. [Melatonin and epilepsy]. PubMed
183. [183] Liat Ayalon et al.. Chronobiol Int. 2002. Case study of circadian rhythm sleep disorder following haloperidol treatment: reversal by risperidone and melatonin. doi:10.1081/cbi-120014105 PubMed
184. [184] Daniel P Cardinali et al.. Neuro Endocrinol Lett. 2002. Melatonin in sleep disorders and jet-lag. PubMed
185. [185] A Herxheimer et al.. Cochrane Database Syst Rev. 2001. Melatonin for preventing and treating jet lag. doi:10.1002/14651858.CD001520 PubMed
186. [186] N Zisapel. CNS Drugs. 2001. Circadian rhythm sleep disorders: pathophysiology and potential approaches to management. doi:10.2165/00023210-200115040-00005 PubMed
187. [187] C K Sen et al.. Am J Clin Nutr. 2000. Thiol homeostasis and supplements in physical exercise. doi:10.1093/ajcn/72.2.653S PubMed
188. [188] S Carranza-Lira et al.. Med Sci Monit. 2000. Melatonin and climactery. PubMed
189. [189] M M Jan. Pediatr Neurol. 2000. Melatonin for the treatment of handicapped children with severe sleep disorders. doi:10.1016/s0887-8994(00)00188-0 PubMed
190. [190] S W Lockley et al.. Sleep. 1999. Sleep and activity rhythms are related to circadian phase in the blind. doi:10.1093/sleep/22.5.616 PubMed
191. [191] S Merali et al.. Proc Natl Acad Sci U S A. 1999. Continuous axenic cultivation of Pneumocystis carinii. doi:10.1073/pnas.96.5.2402 PubMed
192. [192] L Wetterberg. Reprod Nutr Dev. 1999. Melatonin and clinical application. doi:10.1051/rnd:19990309 PubMed
193. [193] DR Wagner. Curr Treat Options Neurol. 1999. Circadian Rhythm Sleep Disorders. doi:10.1007/s11940-999-0020-x PubMed
194. [194] A Samel. Eur J Med Res. 1999. Melatonin and jet-lag. PubMed
195. [195] D J Skene et al.. Adv Exp Med Biol. 1999. Use of melatonin in the treatment of phase shift and sleep disorders. doi:10.1007/978-1-4615-4709-9_10 PubMed
196. [196] K Kashihara et al.. Eur J Neurol. 1999. Circadian rhythm sleep disorder associated with pontine lesion. doi:10.1046/j.1468-1331.1999.610099.x PubMed
197. [197] A Ishizaki et al.. No To Hattatsu. 1999. [Usefulness of melatonin for developmental sleep and emotional/behavior disorders--studies of melatonin trial on 50 patients with developmental disorders]. PubMed
198. [198] J Arendt. Rev Reprod. 1998. Melatonin and the pineal gland: influence on mammalian seasonal and circadian physiology. doi:10.1530/ror.0.0030013 PubMed
199. [199] E Nagtegaal et al.. Ther Drug Monit. 1998. Correlation between concentrations of melatonin in saliva and serum in patients with delayed sleep phase syndrome. doi:10.1097/00007691-199804000-00008 PubMed
200. [200] M Siebler et al.. J Neurol. 1998. Therapeutic entrainment of circadian rhythm disorder by melatonin in a non-blind patient. doi:10.1007/s004150050228 PubMed
201. [201] M Sasaki. Nihon Rinsho. 1998. [Jet lag syndrome]. PubMed
202. [202] J Arendt et al.. Chronobiol Int. 1997. Treatment of circadian rhythm disorders--melatonin. doi:10.3109/07420529709001155 PubMed
203. [203] D Lagarde et al.. Med Trop (Mars). 1997. [Jet lag]. PubMed
204. [204] F Castro-Muñozledo et al.. Invest Ophthalmol Vis Sci. 1997. Cultivation of rabbit corneal epithelial cells in serum-free medium. PubMed
205. [205] R J Croughs et al.. Neth J Med. 1996. Melatonin and jet lag. doi:10.1016/0300-2977(96)00038-1 PubMed
206. [206] O Benoit. Rev Prat. 1996. [Sleep-wakefulness rhythm disorders]. PubMed
207. [207] B Enkvetchakul et al.. Poult Sci. 1995. Influence of diethyl maleate and cysteine on tissue glutathione and growth in broiler chickens. doi:10.3382/ps.0740864 PubMed
208. [208] G M Brown. J Psychiatry Neurosci. 1994. Light, melatonin and the sleep-wake cycle. PubMed
209. [209] T Klein et al.. Sleep. 1993. Circadian sleep regulation in the absence of light perception: chronic non-24-hour circadian rhythm sleep disorder in a blind man with … doi:10.1093/sleep/16.4.333 PubMed
210. [210] A Martín-Fontecha et al.. Scand J Immunol. 1992. Transplantation of cultured thymic fragments in congenitally athymic and euthymic rats. Culture with deoxyguanosine or cyclosporin A does not influence … doi:10.1111/j.1365-3083.1992.tb03257.x PubMed
211. [211] S Taketa et al.. Prostate. 1990. Differences in growth requirements between epithelial and stromal cells derived from rat ventral prostate in serum-free primary culture. doi:10.1002/pros.2990170304 PubMed
212. [212] J H Resau et al.. Cytotechnology. 1990. Long-term culture of human esophageal explants and cells. doi:10.1007/BF00365267 PubMed
213. [213] E Fuchs et al.. Cell. 1981. Regulation of terminal differentiation of cultured human keratinocytes by vitamin A. doi:10.1016/0092-8674(81)90169-0 PubMed