Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.

Stephen M Stahl

Review CNS spectrums 2014 13 次引用

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Study Design

研究类型: Review
研究人群: Totally blind individuals with non-24 sleep-wake syndrome

干预措施: Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients. None
对照组: None
主要结局: Non-24 sleep-wake syndrome in blind patients
效应方向: Positive
偏倚风险: Unclear

Abstract

Many individuals with total blindness can develop a circadian rhythm disorder-called non-24 sleep wake syndrome-because they cannot detect light to resynchronize their sleep-wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep-wake clocks.

简要概述

A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in patients with total blindness, resetting their circadian sleep–wake clocks.

Used In Evidence Reviews

A 褪黑素（Melatonin）用于昼夜节律障碍

Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.

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Study Design

Abstract

简要概述

Used In Evidence Reviews

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