Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.
Study Design
- Çalışma Türü
- Review
- Popülasyon
- Totally blind individuals with non-24 sleep-wake syndrome
- Müdahale
- Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients. None
- Karşılaştırıcı
- None
- Birincil Sonuç
- Non-24 sleep-wake syndrome in blind patients
- Etki Yönü
- Positive
- Yanlılık Riski
- Unclear
Abstract
Many individuals with total blindness can develop a circadian rhythm disorder-called non-24 sleep wake syndrome-because they cannot detect light to resynchronize their sleep-wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep-wake clocks.
Kısaca
A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in patients with total blindness, resetting their circadian sleep–wake clocks.
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