Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients.
Study Design
- अध्ययन प्रकार
- Review
- जनसंख्या
- Totally blind individuals with non-24 sleep-wake syndrome
- हस्तक्षेप
- Mechanism of action of tasimelteon in non-24 sleep-wake syndrome: treatment for a circadian rhythm disorder in blind patients. None
- तुलनित्र
- None
- प्राथमिक परिणाम
- Non-24 sleep-wake syndrome in blind patients
- प्रभाव की दिशा
- Positive
- पूर्वाग्रह का जोखिम
- Unclear
Abstract
Many individuals with total blindness can develop a circadian rhythm disorder-called non-24 sleep wake syndrome-because they cannot detect light to resynchronize their sleep-wake cycles. A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in these patients, resetting their circadian sleep-wake clocks.
संक्षेप में
A new melatonin 1 and melatonin 2 agonist tasimelteon improves sleep in patients with total blindness, resetting their circadian sleep–wake clocks.
Used In Evidence Reviews
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