Glisin için Uykusuzluk
A36 çalışmaya (2 meta-analyses, 6 RCTs), toplam 484,248 katılımcıyla dayanmaktadır. 22/36 çalışma olumlu etkiler göstermektedir.
<\/script>\n`;
},
get iframeSnippet() {
const domain = 'sleepcited.com';
const params = 'ingredient\u003Dglycine\u0026condition\u003Dinsomnia';
return ``;
},
get activeSnippet() {
return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet;
},
copySnippet() {
navigator.clipboard.writeText(this.activeSnippet).then(() => {
this.copied = true;
setTimeout(() => { this.copied = false; }, 2000);
});
}
}"
@keydown.escape.window="open = false"
@click.outside="open = false">
A
Sonuç
Glycine is supported by strong evidence as a supplement that may help improve overall sleep quality, with benefits seen in multiple well-designed clinical trials.
- 22 out of 36 studies show positive effects, with 6 RCTs and 2 meta-analyses
- Glycine may promote sleep by lowering core body temperature, a natural sleep trigger
- A 2024 RCT showed collagen peptides (glycine-rich) reduced sleep fragmentation
- Large evidence base of over 484,000 participants across all study types
Key Study Findings
basic science
Lactobacillus reuteri E9 Regulates Sleep Disorders Through Its Metabolite GABA.
Dose: Lactobacillus reuteri E9 (dose not specified)
vs: Placebo
Etki: None
< 0.05
systematic review
n=451
Double-blind
Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According …
Dose: various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa
vs: Placebo
Etki: bruxism: ΔVAS -2.36 vs -1.72; enuresis: median -2.4 nights/week
0.05 (bruxism); < 0.04 (enures
In vitro
The Glycine-Rich Region as a Flexible Molecular Glue Promoting hPrP106-145 Aggregation into β-Sheet Structures.
Dose: None
vs: Placebo
Etki: None
None
basic science
Time-specific study on the efficacy of stems and leaves of Arachis hypogaea L. targeting glycine/serine …
Dose: Arachis hypogaea L. stems and leaves extract
vs: Placebo
Etki: None
None
randomized controlled trial
n=13
1 weeks
Double-blind
Collagen peptide supplementation before bedtime reduces sleep fragmentation and improves cognitive function in physically active …
Dose: 15 g/day collagen peptides (glycine-rich) consumed 1 hour before bedtime for 7 nights
vs: Placebo
Etki: None
0.028
animal experimental
3 weeks
Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.
Dose: None
vs: Placebo
Etki: None
None
Key Statistics
36
Çalışmalar
483763
Katılımcılar
↑
Positive
A
Derece
Referenced Papers
Pharmaceuticals (Basel, Switzerland)
2026
Journal of chemical …
2025
3 atıf
Children (Basel, Switzerland)
2025
Frontiers in bioscience …
2025
Journal of pharmaceutical …
2025
European journal of …
2024
10 atıf
Journal of ethnopharmacology
2024
6 atıf
Human genetics
2023
17 atıf
Neurological sciences : …
2023
9 atıf
International journal of …
2023
8 atıf
Journal of biomolecular …
2023
3 atıf
Journal of the …
2022
55 atıf
Parkinsonian Syndrome with Frontal Lobe Involvement and Anti-Glycine Receptor Antibodies.
Case Report
Brain sciences
2020
12 atıf
BioMed research international
2019
19 atıf
Clinical cancer research …
2018
65 atıf
Leukemia research
2018
35 atıf
Electronic physician
2017
102 atıf
Sleep medicine reviews
2017
99 atıf
BMC psychiatry
2016
26 atıf
Addictive behaviors
2016
3 atıf
Molecular neurobiology
2016
Fitoterapia
2015
55 atıf
Acta biochimica et …
2013
25 atıf
Frontiers in neurology
2012
27 atıf
Psychiatry and clinical …
2011
23 atıf
Human mutation
2009
136 atıf
Interactions of mineralocorticoids and glucocorticoids in epithelial target tissues revisited.
Review
Steroids
2009
11 atıf
Current drug delivery
2009
1 atıf
Nutritional neuroscience
2008
73 atıf
Journal of medical …
2008
33 atıf
British journal of …
2006
351 atıf
Minerva ginecologica
2006
British journal of …
2005
3 atıf
Neurology
2002
56 atıf
Alternative medicine review …
1998
58 atıf
Clinical neuropharmacology
1994
18 atıf
European journal of …
1986
22 atıf
Dosage & Usage
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units
Yaygın Kullanılan Dozajlar
- sleep:
- 3 g, 1 hour before bed
Üst sınır: Not established; studied up to 9 g/day
Araştırmalarda İncelenen Dozajlar
| Dozaj | Süre | Etki | N |
|---|---|---|---|
| Lactobacillus reuteri E9 (dose not specified) | -- | Positive | -- |
| various homoeopathic remedies (complex homoeopathy, Melissa officinalis 12C, individualised homoeopa | -- | Positive | 451 |
| None | -- | Neutral | -- |
| Arachis hypogaea L. stems and leaves extract | -- | Positive | -- |
| 15 g/day collagen peptides (glycine-rich) consumed 1 hour before bedtime for 7 nights | 1 weeks | Positive | 13 |
| None | 3 weeks | Positive | -- |
| not applicable | -- | Neutral | 17 |
| None | -- | Mixed | 482730 |
En iyi alım zamanı: 1 hour before bed
Safety & Side Effects
Bildirilen Yan Etkiler
- ⚠ Nausea
- ⚠ Soft stools
- ⚠ Mild drowsiness
Bilinen Etkileşimler
- ● Clozapine — glycine may reduce effectiveness of this antipsychotic
- ● Antihypertensives — potential additive blood pressure lowering
Tolere edilebilir üst alım: Not established; studied up to 9 g/day
Herhangi bir takviye kullanmaya başlamadan önce mutlaka sağlık uzmanınıza danışın.Herhangi bir takviye başlatmadan önce her zaman sağlık uzmanınıza danışın.
Frequently Asked Questions
Does Glisin help with Uykusuzluk?
Based on 36 studies with 483,763 participants, there is strong evidence from multiple clinical trials that Glisin may support Uykusuzluk management. Our evidence grade is A (Strong Evidence).
How much Glisin should I take for Uykusuzluk?
Studies have used various dosages. A commonly studied range is 3 g, 1 hour before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Glisin?
Reported side effects may include Nausea, Soft stools, Mild drowsiness. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Glisin and Uykusuzluk?
We rate the evidence as Grade A (Strong Evidence). This rating is based on 36 peer-reviewed studies with 483,763 total participants. The overall direction of effect is positive.
Related Evidence
Şu durum için diğer içerikler: Uykusuzluk
Glisin diğer sağlık durumları için
FDA Sorumluluk Reddi: Bu ifadeler Gıda ve İlaç Dairesi (FDA) tarafından değerlendirilmemiştir. Bu web sitesindeki ürünler ve bilgiler herhangi bir hastalığı teşhis etmek, tedavi etmek, iyileştirmek veya önlemek amacıyla tasarlanmamıştır. Sunulan kanıt dereceleri, yayımlanmış hakemli araştırmalarımızın analizine dayanmaktadır ve tıbbi tavsiye niteliği taşımamaktadır. Herhangi bir takviye rejimine başlamadan önce her zaman sağlık uzmanınıza danışın.