Sleep Onset Difficulty
Prevalence: 15-20% of adults report difficulty falling asleep
Evidence-Ranked Ingredients
| Ingredient | Grade | Studies | Direction | |
|---|---|---|---|---|
| Melatonin | A Strong | 30 | Positive | 보기 → |
| L-Theanine | A Strong | 4 | Positive | 보기 → |
| Tryptophan | B Moderate | 19 | Positive | 보기 → |
| GABA | B Moderate | 16 | Positive | 보기 → |
| Ashwagandha | B Moderate | 6 | Positive | 보기 → |
| Valerian Root | B Moderate | 5 | Positive | 보기 → |
| 5-HTP | D Preliminary | 7 | Positive | 보기 → |
| Glycine | D Preliminary | 1 | Mixed | 보기 → |
| Apigenin | D Preliminary | 0 | Neutral | 보기 → |
| Magnesium Glycinate | D Preliminary | 0 | Neutral | 보기 → |
About
Prolonged time to fall asleep (>30 minutes) after lights-out. Often associated with hyperarousal, anxiety, or delayed circadian phase.
Common Symptoms
Lying awake >30 min
Racing thoughts
Physical tension
Clock-watching anxiety
Risk Factors
- Anxiety
- Blue light exposure
- Late caffeine
- Irregular sleep schedule
Frequently Asked Questions
What supplements may help with Sleep Onset Difficulty?
Based on peer-reviewed research, supplements with the strongest evidence for Sleep Onset Difficulty include Melatonin, L-Theanine, Tryptophan, GABA. These have earned Grade A or B ratings from our analysis of clinical studies. Always consult your healthcare provider before starting any supplement.
How is the evidence for Sleep Onset Difficulty supplements graded?
We grade supplements on an A-F scale based on clinical study quality, consistency of results, sample sizes, and study design. Grade A indicates strong evidence from multiple clinical trials, while Grade D indicates preliminary evidence requiring further research.
How many studies on Sleep Onset Difficulty supplements have been reviewed?
Our evidence grades for Sleep Onset Difficulty are based on a total of 88 peer-reviewed studies across 10 ingredients. Studies are sourced from PubMed and include randomized controlled trials, meta-analyses, and other clinical research.
What are common symptoms of Sleep Onset Difficulty?
Common symptoms associated with Sleep Onset Difficulty include Lying awake >30 min, Racing thoughts, Physical tension, Clock-watching anxiety. If you are experiencing these symptoms, consult a healthcare professional for proper diagnosis and treatment options.
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.