California PoppyCalifornia Poppy
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California Poppy
California Poppy
别名: Eschscholzia californica, Golden poppy, Cup of gold
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About
California poppy (Eschscholzia californica) contains protopine and californidine, alkaloids that modulate GABA-A and opioid receptors without the addictive potential of opium poppies. Traditional use for sleep and mild pain is supported by limited but positive clinical evidence.
How It Works
Protopine and allocryptopine bind GABA-A and opioid receptors; californidine inhibits catechol-O-methyltransferase (COMT); mild analgesic and anxiolytic effects.
Evidence For Conditions
Side Effects
- Drowsiness (intended effect)
- Mild diuretic effect
- Potential interaction with drug testing (may cause false positives for opiates, though rare)
Drug & Supplement Interactions
- Sedatives and anxiolytics — additive CNS depression
- MAO inhibitors — theoretical COMT inhibition interaction
- Opioid medications — may potentiate or interfere with opioid effects
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Related Ingredients
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