Fer pour Syndrome des Jambes Sans Repos

Q: Does Fer help with Syndrome des Jambes Sans Repos?

Based on 173 studies with 36,638 participants, there is strong evidence from multiple clinical trials that Fer may support Syndrome des Jambes Sans Repos management. Our evidence grade is A (Strong Evidence).

Q: How much Fer should I take for Syndrome des Jambes Sans Repos?

Studies have used various dosages. A commonly studied range is 65 mg elemental iron if ferritin <75. Always consult your healthcare provider before starting any supplement regimen.

Q: Are there side effects of Fer?

Reported side effects may include Constipation, Nausea, Stomach pain, Dark stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

Q: How strong is the evidence for Fer and Syndrome des Jambes Sans Repos?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 173 peer-reviewed studies with 36,638 total participants. The overall direction of effect is mixed.

Basé sur 65 études (5 meta-analyses) avec 24,923 participants au total. 34/65 études montrent des effets positifs.

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En conclusion

Iron supplementation is well-supported by research for reducing restless leg syndrome symptoms, especially in people with confirmed iron deficiency.

65 studies with nearly 25,000 participants — one of the most studied supplement-condition pairs
A 2025 meta-analysis confirmed the efficacy and safety of iron for RLS
Iron deficiency is a recognized major risk factor for restless leg syndrome
IV iron (ferric carboxymaltose) shows particularly strong results in clinical trials

Key Study Findings

review

[Restless leg syndrome. Diagnosis and treatment].

Dose: various vs: Placebo Effet: None None

case-control n=90

Restless Leg Syndrome and Association with Serum NT Pro-CNP.

Dose: None vs: Placebo Effet: NT pro-CNP significantly lower in RLS vs controls; sensitivity 80%, specificity 88.9%; serum iron lo None

Cohort Study n=58 Open-label

Efficacy and safety of intravenous iron in patients with restless legs syndrome with normal serum …

Dose: 1000 mg ferric carboxymaltose vs: Group A (ferritin <100) vs Group B (ferritin 100-300) Outcome: IRLS severity scale score change Effet: None None

Population: RLS patients with serum ferritin <300 µg/L

review

Restless Leg Syndrome and Pregnancy.

Dose: iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological) vs: Placebo Effet: None None

review

[Restless Legs Syndrome].

Dose: dopamine agonists, iron supplementation, alpha-2-delta ligands vs: Placebo Effet: None None

review

Optimizing Restless Legs Syndrome Care: Integrating Rehabilitation into Multimodal Management.

Dose: None vs: Placebo Effet: None None

Key Statistics

173

Études

36638

Participants

↔

Mixed

Note

Referenced Papers

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Restless Leg Syndrome and Association with Serum NT Pro-CNP. Other

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Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Posologies couramment utilisées

rls:: 65 mg elemental iron if ferritin <75
general:: 18 mg/day (women)

Limite supérieure : 45 mg/day

Posologies étudiées dans la recherche

Posologie	Durée	Effet	N
various	--	Positive	--
None	--	Positive	90
1000 mg ferric carboxymaltose	--	Positive	58
iron supplementation, folate, dopamine agonists (non-pharmacological and pharmacological)	--	Positive	--
dopamine agonists, iron supplementation, alpha-2-delta ligands	--	Positive	--
None	--	Neutral	--
None	--	Mixed	--
None	--	Positive	--

Moment optimal de prise : On an empty stomach with vitamin C; take in the morning, not before bed

Safety & Side Effects

Effets indésirables signalés

⚠ Constipation
⚠ Nausea
⚠ Stomach pain
⚠ Dark stools
⚠ Iron overload risk (hemochromatosis)

Interactions connues

● Antacids and PPIs — reduce iron absorption
● Levothyroxine — iron reduces thyroid medication absorption
● Antibiotics (tetracyclines, fluoroquinolones) — mutual absorption reduction
● Calcium supplements — take separately by 2 hours

Apport maximal tolérable : 45 mg/day

Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.Consultez toujours votre professionnel de santé avant de commencer tout complément alimentaire.

Frequently Asked Questions

Does Fer help with Syndrome des Jambes Sans Repos?

Based on 173 studies with 36,638 participants, there is strong evidence from multiple clinical trials that Fer may support Syndrome des Jambes Sans Repos management. Our evidence grade is A (Strong Evidence).

How much Fer should I take for Syndrome des Jambes Sans Repos?

Studies have used various dosages. A commonly studied range is 65 mg elemental iron if ferritin <75. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Fer?

Reported side effects may include Constipation, Nausea, Stomach pain, Dark stools. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Fer and Syndrome des Jambes Sans Repos?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 173 peer-reviewed studies with 36,638 total participants. The overall direction of effect is mixed.

Related Evidence

Autres ingrédients pour Syndrome des Jambes Sans Repos

Magnesium Glycinate F

Verdict rapide

Basé sur 65 études (5 meta-analyses) avec 24,923 participants au total. 34/65 études montrent des effets positifs.

Evidence Strength92%

High confidence

Synthèse des études

RCT (3)Meta (9)Other (161)

Comparer les alternatives

Découvrez comment d'autres ingrédients se comparent pour cette condition.Découvrez comment d'autres ingrédients se comparent pour cette pathologie.

Voir tous les ingrédients pour Syndrome des Jambes Sans Repos

En savoir plus

Avertissement FDA: Ces déclarations n'ont pas été évaluées par la Food and Drug Administration. Les produits et informations sur ce site ne sont pas destinés à diagnostiquer, traiter, guérir ou prévenir quelque maladie que ce soit. Les notes de preuve présentées sont basées sur notre analyse de la recherche publiée et évaluée par des pairs et ne constituent pas un avis médical. Consultez toujours votre professionnel de santé avant de commencer tout régime de compléments alimentaires.