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Saffron (Crocus sativus) for Anxiety-Related Sleep Problems

D

No studies available.

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The Bottom Line

            
            
No studies available.

            
            
        

    











    
    

        
        

            

  
Key Statistics





            


    

        
0

        
Studies

    

    

        
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Participants

    

    

        
            
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Neutral

    

    

        D

        
Grade

    




        


        
        

        
        
        

            

  
Dosage & Usage





            
mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units


            
            

                
Commonly Used Dosages

                

                    
                    

                        
sleep:

                        
28-30 mg standardized extract (affron or similar), before bed

                    

                    
                

                
                

                    Upper limit: 200 mg/day (higher doses may cause toxicity)
                

                
            

            

            

            
            

                Best taken: With dinner or 1-2 hours before bed
            

            
        

        

        
        
        

            

  
Safety & Side Effects





            

                
                

                    
Reported Side Effects

                    
    
                        
                        
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                            Drowsiness (desired for sleep use)
                        
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                            Dry mouth
                        
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                            Headache and dizziness (rare at standard doses)
                        
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                            Appetite changes
                        
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Known Interactions

                    
    
                        
                        
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                            SSRIs and antidepressants — may have additive serotonergic effects
                        
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                            Anticoagulants — saffron may have mild antiplatelet effects
                        
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                            Blood pressure medications — may enhance hypotensive effects
                        
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                        Tolerable upper intake: 200 mg/day (higher doses may cause toxicity)
                    

                

                
            

            

                Always consult your healthcare provider before starting any supplement.
            

        

        

        
        
        

            

  
Frequently Asked Questions





            




    
    

        
            Does Saffron (Crocus sativus) help with Anxiety-Related Sleep Problems?
            
        
        

            Based on 0 studies with 0 participants, there is preliminary evidence that needs more research that Saffron (Crocus sativus) may support Anxiety-Related Sleep Problems management. Our evidence grade is D (Very Early Research).
        

    

    
    

        
            How much Saffron (Crocus sativus) should I take for Anxiety-Related Sleep Problems?
            
        
        

            Studies have used various dosages. A commonly studied range is 28-30 mg standardized extract (affron or similar), before bed. Always consult your healthcare provider before starting any supplement regimen.
        

    

    
    

        
            Are there side effects of Saffron (Crocus sativus)?
            
        
        

            Reported side effects may include Drowsiness (desired for sleep use), Dry mouth, Headache and dizziness (rare at standard doses), Appetite changes. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
        

    

    
    

        
            How strong is the evidence for Saffron (Crocus sativus) and Anxiety-Related Sleep Problems?
            
        
        

            We rate the evidence as Grade D (Very Early Research). This rating is based on 0 peer-reviewed studies with 0 total participants. The overall direction of effect is neutral.
        

    

    




        

        

        
        
        

            

  
Related Evidence





            

                
                
                

                
                

                    
Saffron (Crocus sativus) for other conditions

                    

                        
                        
                            Insomnia
                            D

                        
                        
                        
                            Menopause-Related Sleep Disturbance
                            D

                        
                        
                    

                

                
            

        

        

    


    
    












    

        FDA Disclaimer:
        These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.