Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats.

R F Laguzzi

Other Brain research 1982 2 citas

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Study Design

Tipo de estudio: Animal study

Intervención: Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats. None
Comparador: Placebo
Dirección del efecto: Positive
Riesgo de sesgo: Moderate

Abstract

In adult rats an anterodorsal bilateral hippocampectomy produced an increase in motor activity without modification of the amount of the different sleep stages. In hippocampectomized rats p-chlorophenylalanine produced an insomnia which can be reversed by 5-HTP. These results show that the insomnia produced by brain serotonin depletion is not a result of the hyperactivity produced by the treatments which cause such depletion.

Used In Evidence Reviews

B 5-HTP para Insomnio

Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats.

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Study Design

Abstract

Used In Evidence Reviews

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