Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats.

R F Laguzzi

Other Brain research 1982 2 цитирований

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Study Design

Тип исследования: Animal study

Вмешательство: Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats. None
Препарат сравнения: Placebo
Направление эффекта: Positive
Риск систематической ошибки: Moderate

Abstract

In adult rats an anterodorsal bilateral hippocampectomy produced an increase in motor activity without modification of the amount of the different sleep stages. In hippocampectomized rats p-chlorophenylalanine produced an insomnia which can be reversed by 5-HTP. These results show that the insomnia produced by brain serotonin depletion is not a result of the hyperactivity produced by the treatments which cause such depletion.

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B 5-HTP для Бессонница

Effects of serotonin synthesis inhibition on sleep in hippocampectomized rats.

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Study Design

Abstract

Used In Evidence Reviews

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