Kava для Hyperarousal and Cognitive Insomnia

Based on 23 studies (4 meta-analyses, 1 RCT) with 2,043 total participants. Results are mixed across studies.

𝕏 LinkedIn

<\/script>\n

`; }, get iframeSnippet() { const domain = 'sleepcited.com'; const params = 'ingredient\u003Dkava\u0026condition\u003Dhyperarousal\u002Dinsomnia'; return ``; }, get activeSnippet() { return this.method === 'script' ? this.scriptSnippet : this.iframeSnippet; }, copySnippet() { navigator.clipboard.writeText(this.activeSnippet).then(() => { this.copied = true; setTimeout(() => { this.copied = false; }, 2000); }); } }" @keydown.escape.window="open = false" @click.outside="open = false">

Embed This Widget

Style

Widget powered by . Free, no account required.

Итог

Based on 23 studies (4 meta-analyses, 1 RCT) with 2,043 total participants. Results are mixed across studies.

Key Study Findings

Case Reports n=1 6 weeks

Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption.

Dose: None или: None Outcome: acute kava dermopathy with sebaceous gland necrosis Эффект: None None

Популяция: 41-year-old Australian woman consuming kava for anxiety and insomnia

Case Reports n=1 Open-label

Severe kava withdrawal managed with phenobarbital.

Dose: None или: None Outcome: Resolution of kava withdrawal symptoms Эффект: None None

Популяция: 45-year-old man with kava and kratom withdrawal

Other Double-blind

The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and …

Dose: AB-free kava extract или: Placebo Outcome: Tobacco cessation via stress/insomnia management Эффект: None None

Популяция: Adult smokers (trial protocol)

Controlled Clinical Trial

Acute oral toxicity, antinociceptive and antimicrobial activities of kava dried extracts and synthetic kavain.

Dose: None или: Vehicle control Outcome: Acute oral toxicity, antinociceptive activity Эффект: None None

Популяция: Animal model

Systematic Review

The Impact of Complementary and Alternative Medicine on Insomnia: A Systematic Review.

Dose: None или: None Outcome: Sleep quality improvement Эффект: None None

Популяция: Insomnia patients

Review

Calm Down With Kava: What Clinicians Need to Know.

Dose: None или: None Outcome: None Эффект: None None

Популяция: Kava users

Key Statistics

Исследования

2043

Участники

↔

Mixed

Оценка

Referenced Papers

Diagnosing Acute Kava Dermopathy: A Case Report of a Characteristic Cutaneous Eruption. Case Report

The Medical journal … 2026

Severe kava withdrawal managed with phenobarbital. Case Report

The American journal … 2025 1 цитирований

The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a … Other

BMC complementary medicine … 2024 1 цитирований

An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava. Review

Journal of clinical … 2022 27 цитирований

The Impact of Complementary and Alternative Medicine on Insomnia: A Systematic Review. Review

Cureus 2022 17 цитирований

Acute oral toxicity, antinociceptive and antimicrobial activities of kava dried extracts and synthetic kavain. Other

Natural product research 2022 3 цитирований

Calm Down With Kava: What Clinicians Need to Know. Other

Journal of psychosocial … 2022 2 цитирований

Nutraceuticals for Sleep Disorders. Review

Combinatorial chemistry & … 2021 16 цитирований

The Veterans Administration and Department of Defense clinical practice guidelines for the diagnosis and management of sleep disorders: what does … Other

Journal of clinical … 2020 17 цитирований

Enzymes and Pathways of Kavain Bioactivation and Biotransformation. Other

Chemical research in … 2019 6 цитирований

Natural Products from Single Plants as Sleep Aids: A Systematic Review. Systematic Review

Journal of medicinal … 2018 19 цитирований

Herbal medicine for insomnia: A systematic review and meta-analysis. Meta-Analysis

Sleep medicine reviews 2015 152 цитирований

Psychophytomedicine: an overview of clinical efficacy and phytopharmacology for treatment of depression, anxiety and insomnia. Review

Holistic nursing practice 2014 10 цитирований

Toxicokinetics of kava. Other

Advances in pharmacological … 2011 79 цитирований

Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways. Other

FASEB journal : … 2010 110 цитирований

Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. Review

Journal of psychopharmacology … 2005 176 цитирований

An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomnia. RCT

Medicine 2005 128 цитирований

Effects of kava-kava extract on the sleep-wake cycle in sleep-disturbed rats. Other

Psychopharmacology 2005 36 цитирований

Safety and efficacy of herbal sedatives in cancer care. Review

Integrative cancer therapies 2004 59 цитирований

Saccade and cognitive impairment associated with kava intoxication. Other

Human psychopharmacology 2003 45 цитирований

Over-the-counter sleeping pills: a survey of use in Hong Kong and a review of their constituents. Review

General hospital psychiatry 2002 38 цитирований

Kava and valerian in the treatment of stress-induced insomnia. Other

Phytotherapy research : … 2001 74 цитирований

Stress-induced insomnia treated with kava and valerian: singly and in combination. Other

Human psychopharmacology 2001 52 цитирований

[Hematogenous contact eczema cause by phytogenic drugs exemplified by kava root extract]. Case Report

Der Hautarzt; Zeitschrift … 1996 22 цитирований

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

Часто используемые дозировки

sleep:: 120-250 mg kavalactones/day, 1-2 hrs before bed

Верхний предел: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Дозировки, изученные в исследованиях

Дозировка	Длительность	Эффект	N
None	6 weeks	Negative	1
None	--	Positive	1
AB-free kava extract	--	Mixed	--
None	--	Positive	--
None	--	Mixed	--
None	--	Mixed	--
None	--	Mixed	--
not specified	--	Positive	--

Лучшее время приёма: 1-2 hours before bed; avoid daily use beyond 3 months without medical supervision

Safety & Side Effects

Зарегистрированные побочные эффекты

⚠ Drowsiness and reduced coordination
⚠ Hepatotoxicity (rare but serious — consult healthcare provider)
⚠ Skin rash (kava dermopathy) with chronic high-dose use
⚠ GI discomfort

Известные взаимодействия

● Alcohol — increased hepatotoxicity risk and CNS depression
● Hepatotoxic medications (acetaminophen, statins) — additive liver stress
● Benzodiazepines and sedatives — additive CNS depression
● CYP450 substrates (2E1, 1A2, 2D6) — kavalactones may inhibit metabolism
● Levodopa and dopaminergic drugs — kava may reduce efficacy

Допустимый верхний уровень потребления: 250 mg kavalactones/day (European guidelines); limited to 3 months continuous use

Всегда консультируйтесь с врачом перед началом приёма любых добавок.Всегда консультируйтесь с лечащим врачом перед началом приёма любой добавки.

Frequently Asked Questions

Does Kava help with Hyperarousal and Cognitive Insomnia?

Based on 23 studies with 2,043 participants, there is strong evidence from multiple clinical trials that Kava may support Hyperarousal and Cognitive Insomnia management. Our evidence grade is A (Strong Evidence).

How much Kava should I take for Hyperarousal and Cognitive Insomnia?

Studies have used various dosages. A commonly studied range is 120-250 mg kavalactones/day, 1-2 hrs before bed. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of Kava?

Reported side effects may include Drowsiness and reduced coordination, Hepatotoxicity (rare but serious — consult healthcare provider), Skin rash (kava dermopathy) with chronic high-dose use, GI discomfort. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for Kava and Hyperarousal and Cognitive Insomnia?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 23 peer-reviewed studies with 2,043 total participants. The overall direction of effect is mixed.

Related Evidence

Другие ингредиенты для Hyperarousal and Cognitive Insomnia

Skullcap B Magnesium L-Threonate D

Kava для других состояний

Бессонница A Проблемы со сном при тревожности A

Краткий вывод

Based on 23 studies (4 meta-analyses, 1 RCT) with 2,043 total participants. Results are mixed across studies.

Evidence Strength92%

High confidence

Разбор исследований

RCT (1)Meta (1)Other (21)

Сравнить альтернативы

Узнайте, как другие ингредиенты сравниваются при данном состоянии.

Посмотреть все ингредиенты для Hyperarousal and Cognitive Insomnia

Узнать больше

Отказ от ответственности FDA: Данные утверждения не были оценены Управлением по санитарному надзору за качеством пищевых продуктов и медикаментов (FDA). Продукты и информация на этом сайте не предназначены для диагностики, лечения, излечения или профилактики каких-либо заболеваний. Представленные оценки доказательности основаны на нашем анализе опубликованных рецензируемых исследований и не являются медицинской консультацией. Всегда консультируйтесь с лечащим врачом перед началом приёма любых добавок.