タルトチェリー：中途覚醒型不眠症

A エビデンス複数の大規模臨床試験が一貫して有意な効果を示しています。

合計7,254名の参加者を対象とした27件の研究（メタアナリシス3件、RCT 11件を含む）に基づく。27件中14件の研究で肯定的な効果が示されている。

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結論

Tart cherry may help some people stay asleep longer, supported by a moderate body of evidence, though results vary and it may not work for everyone.

27 studies including 3 meta-analyses and 11 RCTs — a substantial evidence base
About 52% of studies show positive effects on staying asleep
Contains natural melatonin and anti-inflammatory compounds that may support longer sleep
Effectiveness may vary depending on the person and tart cherry preparation

Key Study Findings

review

Nutritional Supplements for Healthy Aging: A Critical Analysis Review.

Dose: None vs: Placebo 効果: None None

Review

Selenized non-Saccharomyces yeasts and their potential use in fish feed.

Dose: None vs: None Outcome: None 効果: None None

対象集団: None

In Vitro

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact.

Dose: L. plantarum JGR2 serial passages vs: Ancestral strain Outcome: Phenotypic and genomic changes 効果: None None

対象集団: In vitro bacterial culture study

randomized controlled trial n=34 2 weeks Double-blind

Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes …

Dose: Montmorency tart cherry (MTC) powder 500 mg capsule once daily, 1 hour before bed for 14 days vs: Placebo 効果: No significant effects (p > 0.05 for all outcomes) >0.05

Other 12 weeks

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?

Dose: 92% vs: None Outcome: by ICPMS 効果: or 4 None

対象集団: None

Other n=544 12 weeks

Plasma mineral (selenium, zinc or copper) concentrations in the general pregnant population, adjusted for supplement …

Dose: 25 µmol vs: None Outcome: None 効果: None None

対象集団: pregnant women

Key Statistics

研究数

9058

参加者数

↔

Mixed

グレード

Referenced Papers

Nutritional Supplements for Healthy Aging: A Critical Analysis Review. Review

American journal of … 2025 6 件の引用

Selenized non-Saccharomyces yeasts and their potential use in fish feed. Review

Fish physiology and … 2024 5 件の引用

Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or … RCT

Nutrients 2024 1 件の引用

Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact. Other

Journal of applied … 2024 1 件の引用

Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens. Other

Biological trace element … 2021 18 件の引用

Plasma mineral (selenium, zinc or copper) concentrations in the general pregnant population, adjusted for supplement intake, in relation to thyroid … Other

The British journal … 2021 14 件の引用

Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? Other

Physiological reports 2021 3 件の引用

Efficacy, acceptability, and tolerability of all available treatments for insomnia in the elderly: a systematic review and network meta-analysis. Meta-Analysis

Acta psychiatrica Scandinavica 2020 51 件の引用

Performance, carcass characteristics and meat quality of Nellore cattle supplemented with supranutritional doses of sodium selenite or selenium-enriched yeast. Other

Animal : an … 2020 27 件の引用

Influence of selenium yeast on the growth, selenium uptake and mineral composition of Coriolus versicolor mushroom. Other

Journal of basic … 2020 14 件の引用

Selenium Supplementation and Prostate Health in a New Zealand Cohort. Other

Nutrients 2019 15 件の引用

Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. RCT

American journal of … 2018 61 件の引用

Evaluation of selenium in dietary supplements using elemental speciation. Other

Food chemistry 2017 82 件の引用

Toenail selenium levels and prevalence of dyslipidaemia among Korean adults. Other

The British journal … 2017 6 件の引用

Multiple micronutrient supplementation and birth outcomes: The potential importance of selenium. Review

Placenta 2016 23 件の引用

Selenium as a feed supplement for heat-stressed poultry: a review. Review

Biological trace element … 2015 1 件の引用

Dietary supplements for established atopic eczema. Meta-Analysis

The Cochrane database … 2012 130 件の引用

Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. Other

Molecular nutrition & … 2012 65 件の引用

Antioxidant and antitumor activities of selenium- and zinc-enriched oyster mushroom in mice. Other

Biological trace element … 2012 31 件の引用

Selenium or selenium plus folic acid-supplemented diets ameliorate renal oxidation in ethanol-exposed pups. Other

Alcoholism, clinical and … 2012 19 件の引用

Association of selenium status and blood glutathione concentrations in blacks and whites. RCT

Nutrition and cancer 2011 19 件の引用

Nutrients and infertility: an alternative perspective. Review

European review for … 2011 9 件の引用

Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. RCT

Journal of medicinal … 2010 157 件の引用

Selenium in human and animal nutrition: resolved and unresolved issues. A partly historical treatise in commemoration of the fiftieth anniversary … Review

Critical reviews in … 2009

The role of selenium in chronic disease. Review

Nutrition in clinical … 2008 125 件の引用

Effect of selenium- and glutathione-enriched yeast supplementation on a combined atherosclerosis and diabetes hamster model. Other

Journal of agricultural … 2007 44 件の引用

Nutritional selenium supplements: product types, quality, and safety. Review

Journal of the … 2001 237 件の引用

Dosage & Usage

mg = milligrams · mcg = micrograms (1,000× smaller) · IU = International Units

一般的な使用量

sleep:: 480 mL juice or 480 mg concentrate, twice daily

上限量： Not established

研究で検討された用量

用量	期間	効果	N
None	--	Mixed	--
None	--	Neutral	--
L. plantarum JGR2 serial passages	--	Neutral	--
Montmorency tart cherry (MTC) powder 500 mg capsule once daily, 1 hour before bed for 14 days	2 weeks	Neutral	34
92%	12 weeks	Positive	--
25 µmol	12 weeks	Positive	544
0.16 μg	1 weeks	Positive	216
1,300 µg	--	Neutral	--

推奨摂取タイミング： Morning and evening (twice daily dosing studied)

Safety & Side Effects

報告されている副作用

⚠ GI discomfort
⚠ Diarrhea (high sugar content in juice)
⚠ Weight gain from caloric intake

既知の相互作用

● Blood thinners — cherry anthocyanins may have mild antiplatelet effects
● Diabetes medications — juice form contains significant sugars

耐容上限摂取量： Not established

サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。

Frequently Asked Questions

Does タルトチェリー help with 中途覚醒型不眠症?

Based on 27 studies with 9,058 participants, there is strong evidence from multiple clinical trials that タルトチェリー may support 中途覚醒型不眠症 management. Our evidence grade is A (Strong Evidence).

How much タルトチェリー should I take for 中途覚醒型不眠症?

Studies have used various dosages. A commonly studied range is 480 mL juice or 480 mg concentrate, twice daily. Always consult your healthcare provider before starting any supplement regimen.

Are there side effects of タルトチェリー?

Reported side effects may include GI discomfort, Diarrhea (high sugar content in juice), Weight gain from caloric intake. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.

How strong is the evidence for タルトチェリー and 中途覚醒型不眠症?

We rate the evidence as Grade A (Strong Evidence). This rating is based on 27 peer-reviewed studies with 9,058 total participants. The overall direction of effect is mixed.

に関する他の成分：中途覚醒型不眠症

ビタミンD D

タルトチェリー他の症状・状態について

不眠症 A

総合評価

合計7,254名の参加者を対象とした27件の研究（メタアナリシス3件、RCT 11件を含む）に基づく。27件中14件の研究で肯定的な効果が示されている。

Evidence Strength92%

High confidence

研究の内訳

RCT (4)Meta (2)Other (21)

代替成分との比較

この症状に対する他の成分との比較をご覧ください。

に関するすべての成分を見る：中途覚醒型不眠症

詳しく見る

References

[1] Matthew W Kaufman et al.. Am J Lifestyle Med. 2025. Nutritional Supplements for Healthy Aging: A Critical Analysis Review. doi:10.1177/15598276241244725 PubMed
[2] Paola Díaz-Navarrete et al.. Fish Physiol Biochem. 2024. Selenized non-Saccharomyces yeasts and their potential use in fish feed. doi:10.1007/s10695-024-01340-7 PubMed
[3] Robin M Tucker et al.. Nutrients. 2024. Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or … doi:10.3390/nu16234125 PubMed
[4] Sarvesh V Surve et al.. J Appl Microbiol. 2024. Laboratory domestication of Lactiplantibacillus plantarum alters some phenotypic traits but causes non-novel genomic impact. doi:10.1093/jambio/lxae035 PubMed
[5] Tian-Tian Meng et al.. Biol Trace Elem Res. 2021. Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens. doi:10.1007/s12011-020-02349-8 PubMed
[6] Victor Pop et al.. Br J Nutr. 2021. Plasma mineral (selenium, zinc or copper) concentrations in the general pregnant population, adjusted for supplement intake, in relation to thyroid … doi:10.1017/S000711452000255X PubMed
[7] Thomas Castel et al.. Physiol Rep. 2021. Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals? doi:10.14814/phy2.14933 PubMed
[8] M T Samara et al.. Acta Psychiatr Scand. 2020. Efficacy, acceptability, and tolerability of all available treatments for insomnia in the elderly: a systematic review and network meta-analysis. doi:10.1111/acps.13201 PubMed
[9] J S Silva et al.. Animal. 2020. Performance, carcass characteristics and meat quality of Nellore cattle supplemented with supranutritional doses of sodium selenite or selenium-enriched yeast. doi:10.1017/S1751731119001265 PubMed
[10] Dunja Miletić et al.. J Basic Microbiol. 2020. Influence of selenium yeast on the growth, selenium uptake and mineral composition of Coriolus versicolor mushroom. doi:10.1002/jobm.201900520 PubMed
[11] Nishi Karunasinghe et al.. Nutrients. 2019. Selenium Supplementation and Prostate Health in a New Zealand Cohort. doi:10.3390/nu12010002 PubMed
[12] Jack N Losso et al.. Am J Ther. 2018. Pilot Study of the Tart Cherry Juice for the Treatment of Insomnia and Investigation of Mechanisms. doi:10.1097/MJT.0000000000000584 PubMed
[13] Kevin M Kubachka et al.. Food Chem. 2017. Evaluation of selenium in dietary supplements using elemental speciation. doi:10.1016/j.foodchem.2016.08.086 PubMed
[14] Jiyoung Jang et al.. Br J Nutr. 2017. Toenail selenium levels and prevalence of dyslipidaemia among Korean adults. doi:10.1017/S0007114517002343 PubMed
[15] Anthony V Perkins et al.. Placenta. 2016. Multiple micronutrient supplementation and birth outcomes: The potential importance of selenium. doi:10.1016/j.placenta.2016.02.007 PubMed
[16] Mahmood Habibian et al.. Biol Trace Elem Res. 2015. Selenium as a feed supplement for heat-stressed poultry: a review. doi:10.1007/s12011-015-0275-x PubMed
[17] Fiona J Bath-Hextall et al.. Cochrane Database Syst Rev. 2012. Dietary supplements for established atopic eczema. doi:10.1002/14651858.CD005205.pub3 PubMed
[18] Nicole Metes-Kosik et al.. Mol Nutr Food Res. 2012. Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. doi:10.1002/mnfr.201200386 PubMed
[19] Huimin Yan et al.. Biol Trace Elem Res. 2012. Antioxidant and antitumor activities of selenium- and zinc-enriched oyster mushroom in mice. doi:10.1007/s12011-012-9454-1 PubMed
[20] Maria Luisa Ojeda et al.. Alcohol Clin Exp Res. 2012. Selenium or selenium plus folic acid-supplemented diets ameliorate renal oxidation in ethanol-exposed pups. doi:10.1111/j.1530-0277.2012.01788.x PubMed
[21] John P Richie et al.. Nutr Cancer. 2011. Association of selenium status and blood glutathione concentrations in blacks and whites. doi:10.1080/01635581.2011.535967 PubMed
[22] E Papaleo et al.. Eur Rev Med Pharmacol Sci. 2011. Nutrients and infertility: an alternative perspective. PubMed
[23] Wilfred R Pigeon et al.. J Med Food. 2010. Effects of a tart cherry juice beverage on the sleep of older adults with insomnia: a pilot study. doi:10.1089/jmf.2009.0096 PubMed
[24] Gerhard N Schrauzer et al.. Crit Rev Biotechnol. 2009. Selenium in human and animal nutrition: resolved and unresolved issues. A partly historical treatise in commemoration of the fiftieth anniversary … doi:10.1080/07388550902728261 PubMed
[25] Maria G Boosalis. Nutr Clin Pract. 2008. The role of selenium in chronic disease. doi:10.1177/0884533608314532 PubMed
[26] Gabriel A Agbor et al.. J Agric Food Chem. 2007. Effect of selenium- and glutathione-enriched yeast supplementation on a combined atherosclerosis and diabetes hamster model. doi:10.1021/jf0711901 PubMed
[27] G N Schrauzer. J Am Coll Nutr. 2001. Nutritional selenium supplements: product types, quality, and safety. doi:10.1080/07315724.2001.10719007 PubMed

FDAに関する免責事項: これらの記述は米国食品医薬品局（FDA）による評価を受けていません。本ウェブサイトの製品および情報は、疾病の診断、治療、治癒、または予防を目的としたものではありません。表示されているエビデンスグレードは、公開された査読済み研究の分析に基づいており、医療上の助言を構成するものではありません。サプリメントの摂取を開始する前に、必ず医療専門家にご相談ください。