Neuroimaging in Restless Legs Syndrome.

Federica Provini, Giacomo Chiaro

Review Sleep medicine clinics 2015 29 उद्धरण

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Study Design

अध्ययन प्रकार: Review
जनसंख्या: restless legs syndrome patients

हस्तक्षेप: Neuroimaging in Restless Legs Syndrome. None
तुलनित्र: None
प्राथमिक परिणाम: None
प्रभाव की दिशा: Mixed
पूर्वाग्रह का जोखिम: Unclear

Abstract

Neuroimaging studies are of crucial relevance in defining the pathophysiology of restless legs syndrome (RLS). MRI studies showed no structural brain lesions and confirmed a central iron deficiency. Structural and functional studies showed an involvement of the thalamus, sensorimotor cortical areas, and cerebellum in RLS and assessed neurotransmission abnormalities in the dopaminergic and opiate systems. Finally, glutamatergic hyperactivity has been proposed as a cause of disrupted and shortened sleep in RLS. Differences among the results of the studies make it difficult to draw any definitive conclusions, thus, suggesting the need for future research.

संक्षेप में

Differences among the results of the studies make it difficult to draw any definitive conclusions, thus, suggesting the need for future research.

Used In Evidence Reviews

A Iron के लिए Restless Leg Syndrome

Neuroimaging in Restless Legs Syndrome.

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Study Design

Abstract

संक्षेप में

Used In Evidence Reviews

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