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The association of Restless Legs Syndrome with hypertension and cardiovascular disease.

Vasiliki Katsi, Themistoklis Katsimichas, Manolis S Kallistratos, Dora Tsekoura, Thomas Makris et al.
Review Medical science monitor : international medical journal of experimental and clinical research 2014 18 trích dẫn
PubMed DOI
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Study Design

Loại nghiên cứu
Review
Đối tượng nghiên cứu
Patients with restless legs syndrome
Can thiệp
The association of Restless Legs Syndrome with hypertension and cardiovascular disease. None
Đối chứng
None
Kết quả chính
Association of RLS with hypertension and CVD
Xu hướng hiệu quả
Neutral
Nguy cơ sai lệch
Unclear

Abstract

Restless Legs Syndrome (RLS), is a sensory-motor neurological disorder that appears to be surprisingly common in the community. Periodic limb movements in sleep are typically encountered in more than 80% of RLS patients and comprise involuntary muscular jerks in the lower limbs, such as flexion of the knees or ankles.  Iron deficiency and dopaminergic neuronal dysfunction in the central nervous system are currently thought to be the likely pathophysiological culprits. There is evidence linking RLS to hypertension and cardiovascular disease. This short review will first present a synopsis of epidemiological, clinical and pathophysiological data concerning the syndrome, and then information on the possible links between RLS and cardiovascular disorders.

Tóm lược

This short review will first present a synopsis of epidemiological, clinical, and pathophysiological data concerning the syndrome, and then information on the possible links between RLS and cardiovascular disorders.

Used In Evidence Reviews

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