The association of Restless Legs Syndrome with hypertension and cardiovascular disease.

Vasiliki Katsi, Themistoklis Katsimichas, Manolis S Kallistratos, Dora Tsekoura, Thomas Makris et al.

Review Medical science monitor : international medical journal of experimental and clinical research 2014 18 citazioni

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Study Design

Tipo di studio: Review
Popolazione: Patients with restless legs syndrome

Intervento: The association of Restless Legs Syndrome with hypertension and cardiovascular disease. None
Comparatore: None
Esito primario: Association of RLS with hypertension and CVD
Direzione dell'effetto: Neutral
Rischio di bias: Unclear

Abstract

Restless Legs Syndrome (RLS), is a sensory-motor neurological disorder that appears to be surprisingly common in the community. Periodic limb movements in sleep are typically encountered in more than 80% of RLS patients and comprise involuntary muscular jerks in the lower limbs, such as flexion of the knees or ankles. Iron deficiency and dopaminergic neuronal dysfunction in the central nervous system are currently thought to be the likely pathophysiological culprits. There is evidence linking RLS to hypertension and cardiovascular disease. This short review will first present a synopsis of epidemiological, clinical and pathophysiological data concerning the syndrome, and then information on the possible links between RLS and cardiovascular disorders.

TL;DR

This short review will first present a synopsis of epidemiological, clinical, and pathophysiological data concerning the syndrome, and then information on the possible links between RLS and cardiovascular disorders.

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The association of Restless Legs Syndrome with hypertension and cardiovascular disease.

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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