SleepCited

Passionflower

herb

Also known as: Passiflora incarnata, Maypop

About

Passionflower is a climbing vine traditionally used as a calming herb in North and South American folk medicine. Research suggests its flavonoids, particularly chrysin, may support relaxation and sleep by interacting with GABA receptors in the brain.

How It Works

Chrysin and other flavonoids bind GABA-A receptors (benzodiazepine site); increases total GABA levels.

Evidence For Conditions

Condition Grade Studies Participants
Insomnia A Strong 19 2820 Ansehen →
Anxiety-Related Sleep Problems A Strong 9 2619 Ansehen →

Side Effects

  • Drowsiness
  • Dizziness
  • Confusion at high doses
  • Nausea

Drug & Supplement Interactions

  • Sedatives and benzodiazepines — additive CNS depression
  • Blood thinners — passionflower may increase bleeding risk
  • MAOIs — passionflower contains harmala alkaloids

Always inform your healthcare provider about all supplements you take.

Related Ingredients

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.