Phytochemical Profiling, Antioxidant and Anti-Inflammatory Activity of Plants Belonging to the Lavandula Genus.
Study Design
- نوع الدراسة
- Review
- التدخل
- Phytochemical Profiling, Antioxidant and Anti-Inflammatory Activity of Plants Belonging to the Lavandula Genus. None
- المقارن
- Placebo
- اتجاه التأثير
- Positive
- خطر التحيز
- Unclear
Abstract
Lavender is a valuable medicinal plant belonging to the Lamiaceae family. Currently 39 species are known, but only Lavandula angustifolia is a pharmacopoeial raw material. Lavender has a long history of medicinal use and mainly exhibits antioxidant, anti-inflammatory, sedative, antidepressant, spasmolytic, anticholinesterases, antifungal and antibacterial properties. Used internally, it relieves symptoms of mental stress and insomnia and supports digestion. Topical use of lavender in aromatherapy, neuralgia and antiseptics is also known. The constant interest in lavender, and in particular in Lavandula angustifolia, in the field of medicine and pharmacy is evidenced by the growing number of publications. In view of so many studies, it seems important to review traditional and modern extraction techniques that determine the chemical composition responsible for the antioxidant and anti-inflammatory effects of various extracts from the species of the Lavandula genus.
Full Text
Figures
Tables
Table 5
| Type of | Animal Model of Inflammation | Anti-Inflammation | Detection Method | Ref. | |
|---|---|---|---|---|---|
|
| ethanolic macerate, aqueous macerate | Croton-oil-induced ear edema in mice | edema reduction | HPLC | [ |
|
| Soxhlet extraction | - | inhibition of COX enzymes | HPTLC | [ |
|
| hydroethanolic macerate | formalin test in mice | inhibition of COX enzymes | - | [ |
|
| hydromethanolic extracts (ASE) | carrageenan-induced paw edema in mice | decrease expression of iNOS, COX-2, IL-1β | RP-HPLC-DAD-MS | [ |
|
| decrease expression of IL-1β, IL-6, TNF-α, iNOS, COX-2, MMP-9 | ||||
|
| hydroethanolic extract (UAE) | carrageenan-induced paw edema in rats | edema reduction | - | [ |
|
| hydroalcoholic extracts | mouse macrophage-like cell line RAW 264.7 stimulated with LPS | inhibition of NO production | HPLC-DAD-ESI/MSn | [ |
| aqueous extracts (infusions) |
References
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