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Phytochemical Profiling, Antioxidant and Anti-Inflammatory Activity of Plants Belonging to the Lavandula Genus.

Natalia Dobros, Katarzyna Dorota Zawada, Katarzyna Paradowska
Review Molecules (Basel, Switzerland) 2022 67 sitasi
PubMed DOI CC-BY PDF
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Study Design

Jenis Studi
Review
Intervensi
Phytochemical Profiling, Antioxidant and Anti-Inflammatory Activity of Plants Belonging to the Lavandula Genus. None
Pembanding
Placebo
Arah Efek
Positive
Risiko Bias
Unclear

Abstract

Lavender is a valuable medicinal plant belonging to the Lamiaceae family. Currently 39 species are known, but only Lavandula angustifolia is a pharmacopoeial raw material. Lavender has a long history of medicinal use and mainly exhibits antioxidant, anti-inflammatory, sedative, antidepressant, spasmolytic, anticholinesterases, antifungal and antibacterial properties. Used internally, it relieves symptoms of mental stress and insomnia and supports digestion. Topical use of lavender in aromatherapy, neuralgia and antiseptics is also known. The constant interest in lavender, and in particular in Lavandula angustifolia, in the field of medicine and pharmacy is evidenced by the growing number of publications. In view of so many studies, it seems important to review traditional and modern extraction techniques that determine the chemical composition responsible for the antioxidant and anti-inflammatory effects of various extracts from the species of the Lavandula genus.

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Figures

Tables

Table 5

Lavandula SpeciesType ofExtractAnimal Model of InflammationAnti-InflammationEffectDetection MethodRef.
Lavandula multifida ethanolic macerate, aqueous macerateCroton-oil-induced ear edema in miceedema reductionHPLC[7]
Lavandula bipinnata Soxhlet extraction-inhibition of COX enzymesHPTLC[6]
Lavandula officinalis hydroethanolic macerateformalin test in miceinhibition of COX enzymes-[93]
Lavandula dentata hydromethanolic extracts (ASE)carrageenan-induced paw edema in micedecrease expression of iNOS, COX-2, IL-1βRP-HPLC-DAD-MS[5]
Lavandula stoechas decrease expression of IL-1β, IL-6, TNF-α, iNOS, COX-2, MMP-9
Lavandula stoechas hydroethanolic extract (UAE)carrageenan-induced paw edema in ratsedema reduction-[92]
Lavandula pedunculata hydroalcoholic extractsmouse macrophage-like cell line RAW 264.7 stimulated with LPSinhibition of NO productionHPLC-DAD-ESI/MSn[16]
aqueous extracts (infusions)

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