Passionflower
herbAlso known as: Passiflora incarnata, Maypop
About
Passionflower is a climbing vine traditionally used as a calming herb in North and South American folk medicine. Research suggests its flavonoids, particularly chrysin, may support relaxation and sleep by interacting with GABA receptors in the brain.
How It Works
Chrysin and other flavonoids bind GABA-A receptors (benzodiazepine site); increases total GABA levels.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Insomnia | A Strong | 19 | 2820 | View → |
| Anxiety-Related Sleep Problems | A Strong | 9 | 2619 | View → |
Side Effects
- Drowsiness
- Dizziness
- Confusion at high doses
- Nausea
Drug & Supplement Interactions
- Sedatives and benzodiazepines — additive CNS depression
- Blood thinners — passionflower may increase bleeding risk
- MAOIs — passionflower contains harmala alkaloids
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.