Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome.

Galia V Anguelova, Monique H M Vlak, Arthur G Y Kurvers, Roselyne M Rijsman

Review Sleep medicine clinics 2018 21 citations

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Study Design

Study Type: Review
Population: Patients with primary RLS

Intervention: Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome. None
Comparator: None
Primary Outcome: RLS symptom control
Effect Direction: Mixed
Risk of Bias: Unclear

Abstract

This article provides an updated practical guide for the treatment of primary restless legs syndrome (RLS). Articles that appeared after the American Academy of Neurology guideline search were reviewed according to the same evidence rating schedule. We found limited evidence for nonpharmacologic treatment options. In moderate to severe primary RLS, pharmacologic options may be considered, including iron suppletion, an α2δ ligand, a dopamine agonist, a combination of an α2δ ligand and a dopamine agonist, or oxycodone/naloxone. This article includes treatment options in case of augmentation.

TL;DR

This article provides an updated practical guide for the treatment of primary restless legs syndrome and includes treatment options in case of augmentation.

Used In Evidence Reviews

A Iron for Restless Leg Syndrome

Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome.

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Study Design

Abstract

TL;DR

Used In Evidence Reviews

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