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Latest guidelines and advances for treatment of restless legs syndrome.

Christopher J Earley
Review The Journal of clinical psychiatry 2014 12 citations
PubMed DOI
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Study Design

Study Type
Review
Population
Patients with restless legs syndrome
Intervention
Latest guidelines and advances for treatment of restless legs syndrome. None
Comparator
None
Primary Outcome
RLS symptom management
Effect Direction
Positive
Risk of Bias
Unclear

Abstract

Restless legs syndrome (RLS) is a common disorder that can have a considerable impact on a patient's functioning and quality of life. The pharmacologic armamentarium for RLS contains dopamine agonists, a-2d ligands, and opioids, among other agents. Each of these types of drugs has strengths and limitations, and treatment selection should be based on the frequency of RLS symptoms and any accompanying pain. Dopaminergic augmentation, which exacerbates RLS symptoms, is the most common and challenging side effect of long-term RLS treatment with dopamine agonists and requires special clinical consideration. Iron status is also important to the effective management of RLS.

TL;DR

Dopaminergic augmentation, which exacerbates RLS symptoms, is the most common and challenging side effect of long-term RLS treatment with dopamine agonists and requires special clinical consideration.

Used In Evidence Reviews

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