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Restless legs syndrome in multiple sclerosis.

Mariusz Sieminski, Jacek Losy, Markku Partinen
Review Sleep medicine reviews 2015 38 उद्धरण
PubMed DOI
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Study Design

अध्ययन प्रकार
Review
जनसंख्या
restless legs syndrome patients
हस्तक्षेप
Restless legs syndrome in multiple sclerosis. None
तुलनित्र
None
प्राथमिक परिणाम
None
प्रभाव की दिशा
Mixed
पूर्वाग्रह का जोखिम
Unclear

Abstract

Restless legs syndrome (RLS) is a sleep-related sensory-motor disorder characterized by an irresistible urge to move the legs accompanied by unpleasant sensations in the lower extremities. According to many recent studies patients with multiple sclerosis (MS) suffer frequently from symptoms of RLS. The prevalence of RLS in MS patients varies 13.3%-65.1%, which is higher than the prevalence of RLS in people of the same age in the general population. MS patients with RLS have higher scores in the Expanded Disability Status Scale compared to MS patients without RLS. Presence of RLS has a negative impact on sleep quality and fatigue of MS patients. Iron deficiency and chronic inflammation may be factors contributing to development of RLS in MS. The relationship between the course and treatment of MS and RLS requires further prospective studies.

संक्षेप में

The relationship between the course and treatment of MS and RLS requires further prospective studies, and Iron deficiency and chronic inflammation may be factors contributing to development of RLS in MS.

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