**Figure 6.** Figure 1. The iRISA syndrome [76] in addiction is centrally controlled by dopamine in the brain, while asynchronization, presumed to be linked to cue sensitivity in digital addiction [50–54], is centrally controlled by serotonin. A deﬁcit in both neurotransmitters is identiﬁed as a brain correlate of insomnia, anxiety, and depression.

विवरण

The impaired Response Inhibition and Salience Attribution (iRISA) syndrome model is illustrated, showing how dopamine-mediated reward pathways in the brain drive cue sensitivity in digital addiction and contribute to sleep disruption.

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Neurobiological mechanisms linking excessive digital device use to disrupted sleep architecture are outlined, connecting screen-mediated blue light exposure and dopaminergic reward activation to circadian rhythm disturbances.

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Source Paper

Digital Addiction and Sleep.

International journal of environmental research and public health (2022)

PMID: 35682491

DOI: 10.3390/ijerph19116910

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![Figure 6: The impaired Response Inhibition and Salience Attribution (iRISA) syndrome model is illustrated, showing how dopamine-mediated reward pathways in the brain drive cue sensitivity in digital addiction and contribute to sleep disruption.](https://pdfs.citedhealth.com/figures/35682491/101.png)

> Source: Birgitta Dresp-Langley et al. "Digital Addiction and Sleep.." *International journal of environmental research and public health*, 2022. PMID: [35682491](https://pubmed.ncbi.nlm.nih.gov/35682491/)

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  <img src="https://pdfs.citedhealth.com/figures/35682491/101.png" alt="The impaired Response Inhibition and Salience Attribution (iRISA) syndrome model is illustrated, showing how dopamine-mediated reward pathways in the brain drive cue sensitivity in digital addiction and contribute to sleep disruption." />
  <figcaption>Figure 6. The impaired Response Inhibition and Salience Attribution (iRISA) syndrome model is illustrated, showing how dopamine-mediated reward pathways in the brain drive cue sensitivity in digital addiction and contribute to sleep disruption.<br>  Source: Birgitta Dresp-Langley et al. "Digital Addiction and Sleep.." <em>International journal of environmental research and public health</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35682491/">35682491</a></figcaption>
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