Ashwagandha
adaptogenAlso known as: Withania somnifera, Indian ginseng, KSM-66, Sensoril
About
Ashwagandha is an adaptogenic herb from Ayurvedic medicine that may support sleep through stress reduction. Research suggests its withanolides help modulate cortisol levels and GABA receptors, potentially improving both sleep onset and overall sleep quality.
How It Works
Withanolides modulate GABA-A receptors and reduce cortisol; triethylene glycol (TEG) identified as sleep-inducing component.
Evidence For Conditions
| Condition | Grade | Studies | Participants | |
|---|---|---|---|---|
| Insomnia | A Strong | 29 | 1710 | Afficher → |
| Sleep Onset Difficulty | B Moderate | 6 | 454 | Afficher → |
| Anxiety-Related Sleep Problems | B Moderate | 3 | -- | Afficher → |
Side Effects
- Drowsiness
- GI upset
- Diarrhea
- Headache
Drug & Supplement Interactions
- Thyroid medications — ashwagandha may increase thyroid hormone levels
- Immunosuppressants — ashwagandha may stimulate immune activity
- Sedatives — potential additive drowsiness
- Blood sugar medications — may lower blood glucose
Always inform your healthcare provider about all supplements you take.
Related Ingredients
FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.