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Restless legs syndrome.

William G Ondo
Review Current neurology and neuroscience reports 2005 15 次引用
PubMed DOI
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Study Design

研究类型
Review
研究人群
RLS patients
干预措施
Restless legs syndrome. Dopaminergic medications
对照组
None
主要结局
RLS symptom relief
效应方向
Positive
偏倚风险
Unclear

Abstract

Restless legs syndrome is a very common and still under-diagnosed neurologic condition that can cause severe morbidity. The pathology centers around central nervous system iron homeostatic dysregulation with subsequent alterations in dopaminergic functioning. Genetic studies will hopefully soon identify specific abnormalities. Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

简要概述

Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

Used In Evidence Reviews

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