SleepCited

Management of insomnia: a place for traditional herbal remedies.

Other Prescrire international 2005

Thiết kế nghiên cứu

Loại nghiên cứu
review
Đối tượng nghiên cứu
General population with minor to moderate sleep disturbances; review assessing approximately 20 plants approved in France for traditional use in sleep disorders, focusing on valerian, linden, vervain, melissa, orange flower, hawthorn, passiflora
Can thiệp
Management of insomnia: a place for traditional herbal remedies. variable herbal extract doses
Đối chứng
placebo
Kết quả chính
Efficacy and safety of traditional herbal remedies for insomnia
Xu hướng hiệu quả
Mixed
Nguy cơ sai lệch
Moderate

Tóm tắt

(1) Insomnia should be treated first with non drug measures; this has traditionally involved the use of herbal remedies. (2) About 20 plants are approved in France in the production of medications 'traditionally used' for minor sleep disturbances. Virtually nothing is known of their efficacy or potential dangers. (3) Most of these plants are suspected of toxicity and should therefore be avoided, especially in view of their unproven efficacy. (4) Littleleaf linden, vervain, melissa and orange flower have no demonstrated efficacy but are safe and can therefore be used. Similarly, there are no scientific grounds for rejecting preparations based on hawthorn or passiflora. (5) Available data suggest that valerian extracts have a modest impact on subjective sleep quality; they are nevertheless more effective than a placebo. Valerian products that do not contain valepotriates have no apparent adverse effects. It is best to avoid high-titre alcoholic extracts and powdered valerian root, and to select aqueous extracts and low-titre hydro-alcoholic preparations.

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