Fig. 4

![Fig. 4: Analysis of L-tryptophan intermediate accumulation and its relationship to 5-HTP yield in engineered E. coli strains. Minimizing tryptophan overflow is a critical factor in maximizing conversion efficiency to 5-HTP.](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509612/bin/12934_2022_1920_Fig4_HTML.jpg)

> Source: Zhen Zhang et al. "Metabolic engineering of Escherichia coli for efficient production of L-5-hydrox." *Microbial cell factories*, 2022. PMID: [36153615](https://pubmed.ncbi.nlm.nih.gov/36153615/)

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  <img src="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509612/bin/12934_2022_1920_Fig4_HTML.jpg" alt="Analysis of L-tryptophan intermediate accumulation and its relationship to 5-HTP yield in engineered E. coli strains. Minimizing tryptophan overflow is a critical factor in maximizing conversion efficiency to 5-HTP." />
  <figcaption>Fig. 4. Analysis of L-tryptophan intermediate accumulation and its relationship to 5-HTP yield in engineered E. coli strains. Minimizing tryptophan overflow is a critical factor in maximizing conversion efficiency to 5-HTP.<br>  Source: Zhen Zhang et al. "Metabolic engineering of Escherichia coli for efficient production of L-5-hydrox." <em>Microbial cell factories</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36153615/">36153615</a></figcaption>
</figure>