Light, melatonin and the sleep-wake cycle.

G M Brown

Review Journal of psychiatry & neuroscience : JPN 1994 118 件の引用

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Study Design

研究タイプ: Review
対象集団: general population

介入: Light, melatonin and the sleep-wake cycle. None
比較対照: None
主要アウトカム: sleep quality
効果の方向: Positive
バイアスリスク: Unclear

Abstract

Blood levels of the pineal hormone melatonin are high at night and low during the day. Its secretion is regulated by a rhythm-generating system located in the suprachiasmatic nucleus of the hypothalamus, which is in turn regulated by light. Melatonin is regulated not only by that circadian oscillator but acts as a darkness signal, providing feedback to the oscillator. Melatonin has both a soporific effect and an ability to entrain the sleep-wake rhythm. It also has a major role in regulating the body temperature rhythm. Melatonin rhythms are altered in a variety of circadian rhythm disorders. Melatonin treatment has been reported to be effective in treatment of disorders such as jet lag and delayed sleep phase syndrome.

要約

Melatonin treatment has been reported to be effective in treatment of disorders such as jet lag and delayed sleep phase syndrome and acts as a darkness signal, providing feedback to the oscillator.

Used In Evidence Reviews

A メラトニン：概日リズム障害

A メラトニン：時差ぼけ

Light, melatonin and the sleep-wake cycle.

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Study Design

Abstract

要約

Used In Evidence Reviews

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