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Tutti 5-HTP Acidi grassi Omega-3 Apigenin Ashwagandha Basilico sacro CBD Ferro GABA Lavanda Magnesio glicinato Melatonin Passiflora Radice di valeriana Triptofano Vitamina B6 Vitamina D Zinco Kava
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Number of night awakenings (average)
Figure 5

Number of night awakenings (average)

Evaluation of effectiveness and safety of a herbal compound in primary insomnia …

Figure 1
Figure 1

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Figure 2
Figure 2

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Figure 3
Figure 3

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Figure 4
Figure 4

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c GABA 60 10 9/14 64.29 21.55 ± 0.52bc 5-HTP 6 10 8/14 57.14 25.88 ± 1.05ab Combined G
Figure 5

Group Dose (mg/kg) Caffeine (mg/kg) No. falling sleep/total Sleep onset (%) Sleep duration (min) Normal 0 0 6/13 46.15 29.72 ± 2.13a Control 0 10 6/15 40.00 16.40 ± 0.49c …

Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.

Fig. 1 A Study procedures flow diagram. B Timing of dosing and measurements of endpoints
Figure 6 Flowchart

The study procedures flow diagram and dosing schedule illustrate participant progression through the open-label trial with randomization between cannabis, oxycodone, and combination arms.

Cannabis-opioid interaction in the treatment of fibromyalgia pain: an open-label, proof of …

Figure 1
Figure 1

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 3. Effect of vitamin B6 on the mRNA expression of intestinal barrier function of heat-stressed broilers. Data are presented as mean § SEM (n = 10). Mean values of the TN group and HS group with * differ significantly (P < 0.05). Mean values of th
Figure 2

Figure 3. Effect of vitamin B6 on the mRNA expression of intestinal barrier function of heat-stressed broilers. Data are presented as mean § SEM (n = 10). Mean values of …

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 4. Effect of vitamin B6 on the composition of gut microbiota in the ileum mucosa of heat-stressed broilers. (A) a diversity indices (Chao1, Shannon, Simpson). (B) Non-metric multidimensional scaling (NMDS) plot. (C) Venn plot. * Represents significa
Figure 3

Figure 4. Effect of vitamin B6 on the composition of gut microbiota in the ileum mucosa of heat-stressed broilers. (A) a diversity indices (Chao1, Shannon, Simpson). (B) Non-metric multidimensional scaling …

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 5. Differences in the bacterial communities of ileum mucosa determined by LEfSe analysis and MetaStat analysis. (A) The microbial community at the phylum level. (B) The microbial community at the genus level. (C) The significant differential microbi
Figure 4

Figure 5. Differences in the bacterial communities of ileum mucosa determined by LEfSe analysis and MetaStat analysis. (A) The microbial community at the phylum level. (B) The microbial community at …

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 6. Effect of vitamin B6 on the ileum mucosa metabolites of heat-stressed broilers. (A-B) Partial least squares-discriminant analysis (PLS-DA) score plot. (C-D) PLS-DA valid plot. (E) Pie chart of identified metabolites classification. (F) Venn plot.
Figure 5

Figure 6. Effect of vitamin B6 on the ileum mucosa metabolites of heat-stressed broilers. (A-B) Partial least squares-discriminant analysis (PLS-DA) score plot. (C-D) PLS-DA valid plot. (E) Pie chart of …

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 7. Spearman correlation among ileal differential metabolites with FC > 2, differential microbiota at the phylum and genus levels, differential gut barrier parameters and inflammatory cytokines. The red circle represents a positive correlation and
Figure 6

Figure 7. Spearman correlation among ileal differential metabolites with FC > 2, differential microbiota at the phylum and genus levels, differential gut barrier parameters and inflammatory cytokines. The red circle …

Dietary vitamin B6 supplementation alleviates heat stress-induced intestinal barrier impairment by regulating …

Figure 6
Figure 6

Study on gut microbiota and metabolomics in postmenopausal women.

Figure 7
Figure 7

Study on gut microbiota and metabolomics in postmenopausal women.

Figure 8
Figure 8

Study on gut microbiota and metabolomics in postmenopausal women.

Figure 9
Figure 9

Study on gut microbiota and metabolomics in postmenopausal women.

Fig. 5 The relationship between gut microbiota and gut metabolism, with red and yellow indicating positive correlation and green indicating negative correlation. The significance of the chart is represented as follows: P < 0.01 * *, P < 0.5*
Figure 10

Fig. 5 The relationship between gut microbiota and gut metabolism, with red and yellow indicating positive correlation and green indicating negative correlation. The significance of the chart is represented as …

Study on gut microbiota and metabolomics in postmenopausal women.

Fig 1. Sphere-forming efficiency decreases following radiation. A single 5 Gy dose of radiation (IR d30) was given to 4–6 week old female FVB mice and parotid glands were collected 30 days following radiation for sphere formation assay. Representative bri
Figure 2 Chart

Sphere-forming efficiency of parotid-derived cells decreases significantly following a single 5 Gy radiation dose, quantified at day 30 post-irradiation.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

Fig 2. Similar proliferation rates are observed in untreated and irradiated salispheres cultured in serum-free conditions. Untreated and irradiated parotid-derived salispheres were fixed after 7 and 14 days in culture and stained for Ki-67 (green). Repres
Figure 3 Chart

Proliferation rates of salisphere cultures from untreated and irradiated parotid glands are compared under serum-free conditions, showing similar growth kinetics despite radiation damage.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

Fig 3. FBS increases sphere-forming efficiency of irradiated parotid-derived cells. Representative bright field images of salispheres grown from UT (untreated) and IR d30 (irradiated) glands in serum-free media, supplemented with different concentrations
Figure 4 Photograph

Fetal bovine serum supplementation increases the sphere-forming efficiency of irradiated parotid-derived cells, as shown by representative bright-field microscopy images and quantification.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

Fig 4. Similar proliferation rates are observed in untreated and irradiated salisphere cultures supplemented with FBS. Untreated and irradiated parotid-derived salispheres, maintained under different FBS concentrations, were fixed after 4 and 7 days in cu
Figure 5 Chart

Proliferation assays confirm comparable growth rates between untreated and irradiated salisphere cultures supplemented with FBS, indicating that reduced sphere formation is not due to proliferation deficits.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

Fig 5. Expression of salivary stem/progenitor markers by salisphere cells. Untreated and irradiated parotid-derived salispheres, maintained under different FBS concentrations, were fixed after 7 days in culture and stained for Keratin 5 (K5) or Keratin 14
Figure 6 Chart

Expression of salivary stem and progenitor cell markers in salisphere cultures demonstrates that both untreated and irradiated cells maintain their progenitor phenotype.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

Fig 6. Post-radiation treatment with IGF1 increases sphere-forming efficiency of irradiated parotid-derived cells. A single 5 Gy dose of radiation was given to 4–6 week old or 8 week female FVB mice followed by injections of insulin growth factor 1 (IGF1)
Figure 7 Chart

Post-radiation IGF-1 treatment significantly enhances sphere-forming efficiency of irradiated parotid cells, suggesting growth factor administration as a strategy to restore salivary function.

Administration of growth factors promotes salisphere formation from irradiated parotid salivary glands.

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