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Psychoactive mechanisms of kavalactones are illustrated, showing how these compounds interact with GABAergic, dopaminergic, and noradrenergic neurotransmitter systems to produce anxiolytic and sedative effects.

Figure 2

Diagram

Source Paper

An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava.

Journal of clinical medicine (2022)

PMID: 35887801

DOI: 10.3390/jcm11144039

Cite This Figure

![Figure 2: Psychoactive mechanisms of kavalactones are illustrated, showing how these compounds interact with GABAergic, dopaminergic, and noradrenergic neurotransmitter systems to produce anxiolytic and sedative effects.]()

> Source: Rita B Soares et al. "An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava.." *Journal of clinical medicine*, 2022. PMID: [35887801](https://pubmed.ncbi.nlm.nih.gov/35887801/)
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  <img src="" alt="Psychoactive mechanisms of kavalactones are illustrated, showing how these compounds interact with GABAergic, dopaminergic, and noradrenergic neurotransmitter systems to produce anxiolytic and sedative effects." />
  <figcaption>Figure 2. Psychoactive mechanisms of kavalactones are illustrated, showing how these compounds interact with GABAergic, dopaminergic, and noradrenergic neurotransmitter systems to produce anxiolytic and sedative effects.<br>  Source: Rita B Soares et al. "An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava.." <em>Journal of clinical medicine</em>, 2022. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/35887801/">35887801</a></figcaption>
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