SleepCited

Magnesium Glycinate for Insomnia

A Strong

Based on 9 studies (1 meta-analysis, 2 RCTs) with 2,998 total participants. 6/9 studies show positive effects.

Key Statistics

9

Studies

2998

Participants

Positive

A Strong

Grade

Referenced Papers

Dosage & Usage

Commonly Used Dosages

general:
200-400 mg elemental Mg, before bed

Upper limit: 350 mg/day (supplemental Mg)

Dosages Studied in Research

Dosage Duration Effect N
None -- Mixed --
None -- Mixed --
tryptophan, carbohydrates, omega-3, vitamins (B6, B12, folate, niacin, D, C, beta-carotene), mineral -- Positive --
T1: placebo; T2: magnesium; T3: potassium; T4: magnesium + potassium combination (doses not specifie 8 weeks Positive 290
varies by supplement -- Positive --
1 tablet/day: soy isoflavones 60mg + lactobacilli 500M spores + calcium 141mg + vitamin D3 5mcg + Ma 24 weeks Positive 89
various (passionflower, valerian, chamomile, melatonin, kava, etc.) -- Mixed --

Best taken: 30-60 minutes before bed

Safety & Side Effects

Reported Side Effects

  • Loose stools or diarrhea
  • Nausea
  • Abdominal cramping
  • Low blood pressure at high doses

Known Interactions

  • Antibiotics (tetracyclines, fluoroquinolones) — may reduce absorption
  • Bisphosphonates — magnesium may decrease efficacy
  • Blood pressure medications — additive hypotensive effects

Tolerable upper intake: 350 mg/day (supplemental Mg)

Always consult your healthcare provider before starting any supplement.

Frequently Asked Questions

Does Magnesium Glycinate help with Insomnia?
Based on 9 studies with 2,998 participants, there is strong evidence from multiple clinical trials that Magnesium Glycinate may support Insomnia management. Our evidence grade is A (Strong).
How much Magnesium Glycinate should I take for Insomnia?
Studies have used various dosages. A commonly studied range is 200-400 mg elemental Mg, before bed. Always consult your healthcare provider before starting any supplement regimen.
Are there side effects of Magnesium Glycinate?
Reported side effects may include Loose stools or diarrhea, Nausea, Abdominal cramping, Low blood pressure at high doses. Most side effects are mild and dose-dependent. Consult your doctor if you experience any adverse reactions.
How strong is the evidence for Magnesium Glycinate and Insomnia?
We rate the evidence as Grade A (Strong). This rating is based on 9 peer-reviewed studies with 2,998 total participants. The overall direction of effect is positive.

Related Evidence

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The products and information on this website are not intended to diagnose, treat, cure, or prevent any disease. The evidence grades presented are based on our analysis of published peer-reviewed research and do not constitute medical advice. Always consult your healthcare provider before starting any supplement regimen.