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Carcinosarcoma of the skin. Case report and literature review.

W Biernat, R Kordek, P P Liberski, L Woźniak
Case Report The American Journal of dermatopathology 1996 1 citas
PubMed DOI
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Study Design

Tipo de estudio
Case Reports
Población
cancer patients
Intervención
Carcinosarcoma of the skin. Case report and literature review. None
Comparador
None
Resultado primario
skin outcomes
Dirección del efecto
Mixed
Riesgo de sesgo
High

Abstract

A case of carcinosarcoma arising in the skin of the left arm of a 69-year-old woman is reported with a review of the literature. The tumor was composed of low-differentiated squamous cell carcinoma, which was intermingled with a pleomorphic sarcoma. The carcinomatous component had keratin and lacked vimentin, whereas the phenotype of the sarcomatous portion was the reverse. The former presented additionally focal expression of S-100 protein, which was lacking in other portions of the carcinoma. The phenotypic data, supplemented by p53 immunostaining, which was present in both components, suggest their common origin in this tumor.

TL;DR

The phenotypic data, supplemented by p53 immunostaining, which was present in both components, suggest their common origin in this tumor.

Used In Evidence Reviews

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