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Predictive factors of restless leg syndrome in hemodialysis patients.

Adel Eftekhari, Khadijeh Nasiriani, Samaneh Mirzaei, Somayeh Azimpour Ardakani
Other Journal of renal injury prevention 2016 2 citas
PubMed DOI CC-BY PDF
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Study Design

Tipo de estudio
Cross-sectional
Tamaño de muestra
104
Intervención
Predictive factors of restless leg syndrome in hemodialysis patients. None
Comparador
Placebo
Dirección del efecto
Positive
Riesgo de sesgo
Moderate

Abstract

INTRODUCTION: The restless leg syndrome (RLS) is a neurologic disorder suffering the hemodialysis patients. Although the pathophysiology of this syndrome remains unknown yet, an investigation of the parameters pertinent to it may help to develop the related medical knowledge and to improve the therapeutic-care interventions in this regard. OBJECTIVES: The correlation between the RLSs on individual, clinical, and laboratory indices in patients undergoing hemodialysis. PATIENTS AND METHODS: This descriptive-analytic study was conducted on 104 hemodialysis patients. Diagnosis of RLS was made using the International RLS Standard Questionnaire. The data on individual, clinical, and laboratory indices were obtained from patients' recorded files and interviews. RESULTS: Based on our findings, 28.8% of the patients undergoing hemodialysis were affected with mild RLS, 41.7% with moderate RLS, and 29.5% with severe RLS. There was a statistically significant correlation between affliction with RLS on the one hand, and age and gender, on the other (P < 0.05). However, there was no significant correlation between RLS and education level, occupation, length of hemodialysis, fasting blood sugar (FBS), hepatitis B and C, serum blood urea nitrogen (BUN), creatinine (Cr), iron, hemoglobin (Hb) level and also KT/Vor URR (P < 0.05). CONCLUSION: Regarding the high prevalence of RLS among the hemodialysis patients, there is the necessity for taking more care of these patients to reduce the somatic complications of the RLS especially among the elderly and female patients and to control the blood sugar of these patients at the normal level.

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Tables

Table 1

Number Mild RLS Moderate RLS Severe RLS P
Gender 0.004
Male7 (17.5%)26 (44.8%)21 (51.2%)
Female33 (82.5%)32 (55.2%)20 (48.8%)
Age group 0.032
15-407 (17.5%)7 (17.1%)3 (5.2%)
40-6015 (37.5%)8 (19.5%)27 (46.6%)
60+18 (45.0%)26 (63.4%)28 (48.3%)

Table 2

Variable Mild RLS (n=40) Moderate RLS (n=58) Severe RLS (n=41) P
FBS (mg/dL)124.35146.90158.240.077
BUN (mg/dL)139.57126.92125.440.256
Cr (mg/dL)8.0927.1587.4100.193
Iron (ng/dL)71.3282.4770.460.602
Hb (g/dL)10.74710.45910.9730.349
Kt/V1.1981.1341.2250.238
URR (%)63.9363.6463.660.988

Table 3

Type of diseases Mild RLS Moderate RLS Severe RLS P
Diabetes19 (47.5%)32 (55.2%)23 (56.1%)0.687
Hypertension22 (55%)35 (60.3%)25 (61.0%)0.829
Cardiovascular4 (10.0%)7 (12.1%)4 (9.8%)0.919
Hepatitis B2 (5.0%)1 (1.7%)1 (2.4%)0.622
Hepatitis C1 (2.4%)2 (5.0%)0 (0.0%)0.244

References

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