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Restless legs syndrome.

William G Ondo
Review Current neurology and neuroscience reports 2005 15 citas
PubMed DOI
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Study Design

Tipo de estudio
Review
Población
RLS patients
Intervención
Restless legs syndrome. Dopaminergic medications
Comparador
None
Resultado primario
RLS symptom relief
Dirección del efecto
Positive
Riesgo de sesgo
Unclear

Abstract

Restless legs syndrome is a very common and still under-diagnosed neurologic condition that can cause severe morbidity. The pathology centers around central nervous system iron homeostatic dysregulation with subsequent alterations in dopaminergic functioning. Genetic studies will hopefully soon identify specific abnormalities. Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

TL;DR

Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

Used In Evidence Reviews

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