Descripción

Luciferase reporter assay results confirm that BMAL1 overexpression activates MUC4 promoter activity in a dose-dependent manner, while BMAL1 knockdown reduces promoter activity below baseline levels.

Figure 8

Chart

Source Paper

Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during dry eye development.

Experimental & molecular medicine (2024)

PMID: 38956298

DOI: 10.1038/s12276-024-01269-0

Cite This Figure

![Figure 8: Luciferase reporter assay results confirm that BMAL1 overexpression activates MUC4 promoter activity in a dose-dependent manner, while BMAL1 knockdown reduces promoter activity below baseline levels.]()

> Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." *Experimental & molecular medicine*, 2024. PMID: [38956298](https://pubmed.ncbi.nlm.nih.gov/38956298/)

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  <img src="" alt="Luciferase reporter assay results confirm that BMAL1 overexpression activates MUC4 promoter activity in a dose-dependent manner, while BMAL1 knockdown reduces promoter activity below baseline levels." />
  <figcaption>Figure 8. Luciferase reporter assay results confirm that BMAL1 overexpression activates MUC4 promoter activity in a dose-dependent manner, while BMAL1 knockdown reduces promoter activity below baseline levels.<br>  Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." <em>Experimental & molecular medicine</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38956298/">38956298</a></figcaption>
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