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Restless legs syndrome.

William G Ondo
Review Current neurology and neuroscience reports 2005 15 Zitierungen
PubMed DOI
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Study Design

Studientyp
Review
Population
RLS patients
Intervention
Restless legs syndrome. Dopaminergic medications
Vergleichsgruppe
None
Primärer Endpunkt
RLS symptom relief
Wirkungsrichtung
Positive
Verzerrungsrisiko
Unclear

Abstract

Restless legs syndrome is a very common and still under-diagnosed neurologic condition that can cause severe morbidity. The pathology centers around central nervous system iron homeostatic dysregulation with subsequent alterations in dopaminergic functioning. Genetic studies will hopefully soon identify specific abnormalities. Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

Zusammenfassung

Treatment of restless legs syndrome with dopaminergic medications is highly effective, although augmentation may occur eventually and require dosing flexibility.

Used In Evidence Reviews

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