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Navigating Melatonin Safety: Fact, Fiction, and Confounders.

Alessandro Colitta, Francy Cruz-Sanabria, Simone Bruno, Ugo Faraguna
Other Journal of pineal research 2026
PubMed DOI
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Abstract

As a chronobiotic with sleep-promoting properties, melatonin is frequently recommended by sleep medicine practitioners and widely available as an over-the-counter drug. Recently, two publications questioned melatonin safety profile in insomnia patients, with one of these receiving vast media coverage and noticeable resonance among the general public. This letter to the Editor critically evaluates such research, offering a broader contextualization within the existing body of literature about melatonin safety and insomnia-related health outcomes.

باختصار

This letter to the Editor critically evaluates research on melatonin safety profile in insomnia patients, offering a broader contextualization within the existing body of literature about melatonin safety and insomnia‐related health outcomes.

Used In Evidence Reviews

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