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Rescue experiments demonstrate that BMAL1 overexpression in circadian-disrupted corneal epithelial cells restores MUC4 levels, confirming the causal relationship between clock gene function and mucin production.

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![Figure 14: Rescue experiments demonstrate that BMAL1 overexpression in circadian-disrupted corneal epithelial cells restores MUC4 levels, confirming the causal relationship between clock gene function and mucin production.]()

> Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." *Experimental & molecular medicine*, 2024. PMID: [38956298](https://pubmed.ncbi.nlm.nih.gov/38956298/)
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  <img src="" alt="Rescue experiments demonstrate that BMAL1 overexpression in circadian-disrupted corneal epithelial cells restores MUC4 levels, confirming the causal relationship between clock gene function and mucin production." />
  <figcaption>Figure 14. Rescue experiments demonstrate that BMAL1 overexpression in circadian-disrupted corneal epithelial cells restores MUC4 levels, confirming the causal relationship between clock gene function and mucin production.<br>  Source: Hao Zeng et al. "Circadian disruption reduces MUC4 expression via the clock molecule BMAL1 during." <em>Experimental & molecular medicine</em>, 2024. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/38956298/">38956298</a></figcaption>
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