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Orphan receptor GPR55 modulation by phytocannabinoids is shown in the context of epilepsy. GPR55 antagonism by CBD represents a non-classical cannabinoid mechanism.
Figure 452
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Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy.Cite This Figure
![Figure 452: Orphan receptor GPR55 modulation by phytocannabinoids is shown in the context of epilepsy. GPR55 antagonism by CBD represents a non-classical cannabinoid mechanism.]() > Source: Lara Senn et al. "Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Se." *Pharmaceuticals (Basel, Switzerland)*, 2020. PMID: [32751761](https://pubmed.ncbi.nlm.nih.gov/32751761/)
<figure> <img src="" alt="Orphan receptor GPR55 modulation by phytocannabinoids is shown in the context of epilepsy. GPR55 antagonism by CBD represents a non-classical cannabinoid mechanism." /> <figcaption>Figure 452. Orphan receptor GPR55 modulation by phytocannabinoids is shown in the context of epilepsy. GPR55 antagonism by CBD represents a non-classical cannabinoid mechanism.<br> Source: Lara Senn et al. "Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Se." <em>Pharmaceuticals (Basel, Switzerland)</em>, 2020. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/32751761/">32751761</a></figcaption> </figure>