Sleep Disorders: Circadian Rhythm Sleep-Wake Disorders.
研究设计
- 研究类型
- review
- 研究人群
- Approximately 20% of employed US adults engaged in shift work; travelers crossing at least two time zones; review of circadian rhythm sleep-wake disorders management
- 干预措施
- Sleep Disorders: Circadian Rhythm Sleep-Wake Disorders. melatonin (timed), bright light (timed), stimulants/alertness-promoting drugs
- 对照组
- no treatment or daytime work schedule
- 主要结局
- insomnia, excessive sleepiness in shift workers; jet lag symptoms in travelers
- 效应方向
- Positive
- 偏倚风险
- Unclear
摘要
Shift work sleep disorder is a common problem in industrialized countries because of the need for occupations and services to continue to function 24 hours/day. Approximately 20% of employed adults in the United States are engaged in shift work. Shift work sleep disorder is diagnosed if there is a report of insomnia or excessive sleepiness for at least 3 months associated with a recurring work schedule that overlaps the usual time for sleep. Shift work is associated with an increased occurrence of metabolic disorders, such as insulin resistance, diabetes, dyslipidemia, and metabolic syndrome, and it has been implicated in weight gain and cognitive impairment. There is evidence of increased absenteeism in night workers compared with day workers. A planned sleep schedule, timed bright light exposure, timed melatonin administration, and stimulants or drugs promoting alertness can be used to manage shift work sleep disorder. Jet lag is characterized by a misalignment between internal circadian rhythms and local time caused by rapid travel across at least two time zones. Not all travelers experience jet lag; risk factors include age, number of time zones crossed, and circadian preference. Management includes timed melatonin along with optional timed and dosed bright light exposure.