Management of insomnia: a place for traditional herbal remedies.
研究设计
- 研究类型
- review
- 研究人群
- General population with minor to moderate sleep disturbances; review assessing approximately 20 plants approved in France for traditional use in sleep disorders, focusing on valerian, linden, vervain, melissa, orange flower, hawthorn, passiflora
- 干预措施
- Management of insomnia: a place for traditional herbal remedies. variable herbal extract doses
- 对照组
- placebo
- 主要结局
- Efficacy and safety of traditional herbal remedies for insomnia
- 效应方向
- Mixed
- 偏倚风险
- Moderate
摘要
(1) Insomnia should be treated first with non drug measures; this has traditionally involved the use of herbal remedies. (2) About 20 plants are approved in France in the production of medications 'traditionally used' for minor sleep disturbances. Virtually nothing is known of their efficacy or potential dangers. (3) Most of these plants are suspected of toxicity and should therefore be avoided, especially in view of their unproven efficacy. (4) Littleleaf linden, vervain, melissa and orange flower have no demonstrated efficacy but are safe and can therefore be used. Similarly, there are no scientific grounds for rejecting preparations based on hawthorn or passiflora. (5) Available data suggest that valerian extracts have a modest impact on subjective sleep quality; they are nevertheless more effective than a placebo. Valerian products that do not contain valepotriates have no apparent adverse effects. It is best to avoid high-titre alcoholic extracts and powdered valerian root, and to select aqueous extracts and low-titre hydro-alcoholic preparations.