Mô tả

Pathogenic mechanisms distinguishing C-terminal from N-terminal PRNP mutations are summarized, including differences in disease phenotype, age of onset, and transmission characteristics.

Figure 6

Diagram

Source Paper

Mutations in Prion Protein Gene: Pathogenic Mechanisms in C-Terminal vs. N-Terminal Domain, a Review.

International journal of molecular sciences (2019)

PMID: 31340582

DOI: 10.3390/ijms20143606

Cite This Figure

![Figure 6: Pathogenic mechanisms distinguishing C-terminal from N-terminal PRNP mutations are summarized, including differences in disease phenotype, age of onset, and transmission characteristics.]()

> Source: Livia Bernardi et al. "Mutations in Prion Protein Gene: Pathogenic Mechanisms in C-Terminal vs. N-Termi." *International journal of molecular sciences*, 2019. PMID: [31340582](https://pubmed.ncbi.nlm.nih.gov/31340582/)

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  <img src="" alt="Pathogenic mechanisms distinguishing C-terminal from N-terminal PRNP mutations are summarized, including differences in disease phenotype, age of onset, and transmission characteristics." />
  <figcaption>Figure 6. Pathogenic mechanisms distinguishing C-terminal from N-terminal PRNP mutations are summarized, including differences in disease phenotype, age of onset, and transmission characteristics.<br>  Source: Livia Bernardi et al. "Mutations in Prion Protein Gene: Pathogenic Mechanisms in C-Terminal vs. N-Termi." <em>International journal of molecular sciences</em>, 2019. PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/31340582/">31340582</a></figcaption>
</figure>

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